抗肿瘤作用__(期刊论文)

两种海藻多糖的提取分析及其体外抗肿瘤作用

http://www.100md.com 《广东药学院学报》 2003年第4期

抗肿瘤作用,,匍枝马尾藻；铜藻；提取；分析；抗肿瘤作用,1材料,2方法,3结果与讨论,参考文献

     摘要对采集于湛江硇洲岛的匍枝马尾藻(Sargassum polycystum C)和铜藻( Sargassum horneri )两种海藻进行多糖的热水提取，Sevag法除蛋白，通过紫外和红外光谱相互验证分析，证明其主要为多糖成分，并对其多糖成分进行体外抗肿瘤(人肺腺癌细胞系SPC-A-Ⅰ)作用的初步研究，结果表明，终浓度为0.12%的匍枝马尾藻和铜藻的初筛抑瘤率分别为58.9%和32.9%。

    关键词匍枝马尾藻；铜藻；提取；分析；抗肿瘤作用

    Extraction and measurement of two kinds of seaweed polysaccharides and their antitumor effect in vitro

    LIU Qiuying,MENG Qingyong,LIU Zhihui

    (Analysis Center of Guangdong Medical College,Zhanjiang,Guangdong 524023)

    Abstract Two kinds of seaweed polysaccharides were extracted with hot water from Sargassum polycystum and Sargassum horneri from the seashore of Naozhou in Zhanjiang . The protein was removed by Sevag method. The eluted fractions were analyzed by ultraviolet and IR and the main component was proved to be polysaccharide. Their antitumor effect against SPC-A-Ⅰ was studied in vitro. The results indicated that the antitumor efficiencies of the polysaccharides from Sargassum polycystum and Sargassum horneri were 58.9% and 32.9% respectively in the final concentration of 0.12%. ......

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