母婴传播慢性HBV携带者病程及HBV血清标志物分析
母婴传播,,],母婴传播；慢性；肝炎病毒乙型；丙氨酸氨基转移酶,1方法和材料,2结果,3讨论,参考文献：
[摘要] 目的：探讨母婴传播的慢性无症状乙型肝炎病毒携带者(ASC)病程的变化情况及乙肝病毒血清标志物(HBVM)的表达。方法：对62例母婴传播的慢性无症状乙型肝炎病毒携带者连续10 a～13 a监测其乙型肝炎病毒血清标志物和血清丙氨酸氨基转移酶(ALT)。结果：62例对象中,47例未经任何治疗者在13年中有3例出现ALT升高，3例HBVM模式发生改变。15例经抗病毒治疗者有7例出现ALT升高，只有2例HBVM模式发生改变。结论：经母婴传播的慢性乙型肝炎病毒携带者没有出现明显的三个临床阶段，其乙型肝炎e抗原转换率只有8.1%，对其进行抗病毒治疗反而引起肝细胞破坏。[关键词] 母婴传播；慢性；肝炎病毒乙型；丙氨酸氨基转移酶
Assay the Course of the Mother to Infants Transmission the Chronic Asymptomatic HBV Carrier and the Exhibition of the HBV Serum Sign Matter
LIN Yingqing
(People's Hospital of Nan'ao County, Nan’ao，Guangdong, 515900,China)
Abstract：Objective Discussing the develop of The chronic asymptomatic HBV carrier (ASC) from the mother to infants transmission,and discuss the exhibition of the Hepatitis B Virus Serum Sign Matter(HBVM).Methods To detect the HBVM and ALT of 62 infants who have ASC for a series of ten to thirteen years.Results In these 62 examples,47 infants didn't have any cure for thirteen years and between them 3 infants'ALT haven hoisted and the other 3 infants' HBVM mode have changed,15 infants had therapied by the antivirus,and in between them,7 infants'ALT haven't hoisted,none but 2 infants' HBVM mode have changed.Conclusion The mother to infant transmission ASC from the mothers do not appear three clinic phase in evidence,their Eartigen transform rate ofhepatitis B virus only 8.1%,on the contrary,it will destroy the liver cell if you therapy by the antivirus. ......
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