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贲门腺癌P170蛋白表达的研究
http://www.100md.com 《实用医技杂志》 2006年第2期
贲门肿瘤,,],贲门肿瘤;药物耐受性;基因表达;流动血细胞计数,1材料与方法,2结果,3讨论,参考文献:
     [摘要] 目的:研究并探讨P170蛋白在贲门腺癌组织中的表达及其意义。方法:用流式细胞术检测55例贲门腺癌患者癌组织和距离肿瘤5 cm以上癌旁正常组织P170。结果:55例贲门腺癌组织P170阳性表达率为50.9%,癌旁正常组织未见P170表达,两者差别有统计意义。结论:贲门腺癌组织中具有多药耐药性,检测癌组织P170表达水平对化疗效果有一定意义。

    [关键词] 贲门肿瘤;药物耐受性;基因表达;流动血细胞计数

    Study on P170 Protein Expression in Cardiac Adenocarc Inoma

    PENG Xuehong,Chen Nuan,XU Jianheng,et al

    (The First Affiliated Hospital University,Shantou,Guangdong 515041,China)

    Abstract:Objective To study the expression and signicance of P170 protein in cardiac adenocarcinoma.Methods The expression of P170 protein in 55 cases of cardiac adenocarcinoma was detected by flow cytometry.Results The positive expression rate of P170 protein was 50.9% in 55 cases of cardiac cancer tissue.Normaltissue near cancer has no positive expression of P170 protein.There was an obvious difference between normal and cancer tissue.Conclusion There was multiple drug tolerlance in cardiac adenocarcinoma,detection of P170 protein expression in cancer tissue had significance in evaluation of chemotherapy. ......

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