多重耐药鲍曼不动杆菌____

多重耐药鲍曼不动杆菌β内酰胺酶基因型研究

http://www.100md.com 《实用医技杂志》 2006年第2期

多重耐药鲍曼不动杆菌,,],多重耐药鲍曼不动杆菌;β内酰胺酶;基因型,1材料与方法,2结果,3讨论,参考文献:

     [摘要] 目的：了解我院临床分离的多重耐药鲍曼不动杆菌β内酰胺酶基因分布情况。方法：用三维试验检测15株多重耐药鲍曼不动杆菌ESBLs、AmpC、MBL(金属β内酰胺酶)产酶情况；用PCR方法检测各种β内酰胺酶基因。结果：三维试验检出2株菌产ESBLs；9株菌产AmpC；3株菌合产ESBLs和AmpC酶；3株菌产MBL(均同时产AmpC)。PCR检出15株菌均携带blaTEM基因；2株菌携带blaPER1基因；14株菌携带AmpC基因；未检出产金属β内酰胺酶基因。结论：我院多重耐药的鲍曼不动杆菌多含有blaTEM基因和AmpC基因，也首次发现部分产PER型ESBLs鲍曼不动杆菌。

    [关键词] 多重耐药鲍曼不动杆菌;β内酰胺酶;基因型

    Study on the Genotype of βlactmases in Multiresistant Acinetobacter Baumannii Strain

    CAO Chunyuan

    (Tongling People's Hospital,Tongling，Anhui 244000,China)

    Abstract：Objective To investigate the distribution on genotype of βLactmases in multiresistant acinetobacter baumannii strain isolated from our hospital.Methods Three dimemensional extract tests were performed to detect the strains of ESBLsproducing and AmpCproducing and MBLproducing in 15 Multiresistant Acinetobacter baumannii.The genotype of βLactmases were detected by PCR methods.Results 2 strains ESBLsproducing and 9 strains AmpCproducing,3 strains ESBLsproducing plus AmpCproducing and 3 strains MBLproducing with AmpCproducing have been detected by three dimemensional extract tests.All 15 strains have blaTEM gene and 2 strains have blaPER gene,14 strains have AmpC gene and haven't MBLproducinggene by PCR methods.Conclusion The most multiresistant acinetobacter baumannii have blaTEM and AmpC gene,a little strains have ESBLs of PERtype and no MBL of IMPtype. ......

百拇医药网 http://www.100md.com/html/DirDu/2006/05/31/98/26/40.htm

您现在查看是摘要页，全文长 11875 字符。