内毒素__(期刊论文)

小肠RNA对受60Coγ射线照射后小鼠肠系膜淋巴结细菌移位和血中内毒素含量的影响

http://www.100md.com 《第四军医大学学报》 2006年第9期

内毒素,,小肠;RNA；γ线；内毒素；细菌移位；细胞存活,0引言,1材料和方法,2结果,3讨论,【参考文献】

     Effects of intestinal RNA on MLN bacterial translocation and endotoxin in blood of mice after abdominal 60Coγirradiation

    SU XiaoMing，ZENG GuiYing，REN DongQing，ZHOU XiaoGuang，FANG HengHu，ZHAO Tao，JIN Cheng，XU XiuLi

    Department of Irradiation Medicine，School of Preventive Medicine， Department of Clinical Laboratory，Xijing Hospital，Fourth Military Medical University，Xian 710033，China

    【Abstract】 AIM: To explore the effects of intestinal RNA on MLN bacterial translocation and endotoxin in blood of mice after abdominal 60Coγirradiation. METHODS: The 144 BALB/c male mice were abdominally irradiated with 1150 cGy 60Coγray in 1-3 h， and then they were injected intestinal RNA from normal rats on jejunum. On day 1， 3 and 5 after irradiation，the mice were sacrified after anesthesia for determining endotoxin in blood and bacterial metathetic rate， and intestinal crypt survival rate. RESULTS: Intestinal RNA can decrease MLN bacterial metathetic rate and the level of endotoxin in blood. Intestinal RNA can significantly increase the crypt survival rate of jejunum (P<0.01). CONCLUSION: Intestinal RNA can improve intestinal mucosal mechanical barrier and decrease intestinal bacterial metathetic rate in irradiated mice. ......

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