大环_____铜配合物；大环；超氧化物歧化酶；表征

二十四员大环双核铜(Ⅱ)配合物的合成及其对超氧化物歧化酶的模拟——Ⅰ若干配合物的合成和表征

http://www.100md.com 《广东药学院学报》 2001年第4期

大环,,铜配合物；大环；超氧化物歧化酶；表征,1实验部分,2结果与讨论,参考文献

     摘要合成了以2,6-二乙酰基吡啶缩3-氧戊烷1,5-二胺为配体，以H2O、im-、N-3及SCN-为桥基的四种大环双核铜配合物，所有配合物均用多种物理方法进行表征并推断了它们空间结构。结果表明,随桥联不同，中心原子的配位数也不一样。

    关键词铜配合物；大环；超氧化物歧化酶；表征

    Synthesis of four 24-membered macrocyclic binuclear copper(Ⅱ) complexes and modelling on superoxide dismutase:Ⅰ. Synthesis and characterization of Cu(Ⅱ) complexes

    MEI Guangquan(Department of Chemistry,Yichun College,Yichun,Jiangxi 336000)

    Abstract Four 24-membered macrocyclic binuclear copper(Ⅱ) complexes for modelling Cu,Zn SOD were synthesized by condensation reactions of 2,6-diacetylpyridine with 3-oxapentane-1,5-diamine,in which two metal centers were linked via H2O,im-,N3- or SCN- bridge.All complexes were characterized by several physical methods. The results showed that the coordination number of central atoms varied with different bridging.

    Key words copper complexes;Macrocycle;SOD;Characterization

    超氧离子是人体内的氧代谢产物，它在体内过量积累会引起多种疾病。超氧化物歧化酶对超氧离子起催化作用，以维持机体正常运行，近年来发现许多低分子量的配合物 ......

百拇医药网 http://www.100md.com/html/DirDu/2006/06/20/01/31/68.htm

您现在查看是摘要页，全文长 8712 字符。