【摘要】 电离辐射在工业、医学的广泛应用可造成机体严重造血损伤，造血干细胞移植是救治的重要措施。本文概述了4种造血干细胞移植方法在辐射损伤中的应用，并重点介绍了4种造血干细胞移植的优缺点及研究进展。

     【关键词】 造血干细胞移植;电离辐射;辐射损伤

    The application of hematopoietic stem cells to iradiation injuries WANG Ming-ke，LUO Cheng-ji. The Institute of Combined Injury，The Third Military Medical University，Chongqing 400038，China

    【Abstract】 The application of ionizing radiation to industry，medicine may lead to severe hematopoietic injuries，while hematopoietic stem cells transplantation is the important therapy.In this article four methods of hematopoietic stem cells transplantation in application to radiation injuries are reviewed.Meanwhile，more emphasis is focus on the advantage and disadvantage and research progression of the four methods of hematopoietic stem cells transplantation.

    【Key words】 Hematopoietic stem cell transplantation;Radiation，ionizing;Radiation injuries

    (Chin J Dis Control Prev2006，10(3):295-298)

    电离辐射可引起机体损伤，机体短时间内受到较大剂量(>1Gy)照射后可引起急性放射病。根据照射剂量、病理变化以及临床特点不同，可将放射病分为骨髓型、肠型和脑型。而骨髓型又按其损伤轻重分为轻、中、重和极重度。在骨髓型急性放射病中，造血器官损伤是其最重要的病理改变:细胞和组织退行性变包括变性和死亡;循环障碍 ......