胃黏膜内癌淋巴结微转移的临床意义
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阎庆辉, 刘 津, 史利克, 王凤安, 蔡建辉,
胃黏膜内癌;微转移;Cytokeratin;免疫组织化学阎庆辉,刘津,史利克,王凤安,蔡建辉,池口正英.胃黏膜内癌淋巴结微转移的临床意义. 世界华人消化杂志2006;14(20)2026-
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阎庆辉, 刘津, 史利克, 王凤安, 蔡建辉, 河北医科大学第二医院胃肠外科 河北省石家庄市 050000
池口正英, 日本鸟取大学医学部附属病院第一外科 日本鸟取县米子市 683-8504
通讯作者: 蔡建辉, 050000, 河北省石家庄市和平西路215号, 河北医科大学第二医院胃肠外科. jianhuicai@yahoo.com
电话: 0311-87222983
收稿日期: 2006-04-06 接受日期: 2006-05-22
Clinical significance of micrometastasis in lymph nodes of mucosal gastric cancer
Qing-Hui Yan, Jin Liu, Li-Ke Shi, Feng-An Wang, Jian-Hui Cai, Masahida Ikeguchi
Qing-Hui Yan, Jin Liu, Li-Ke Shi, Feng-An Wang, Jian-Hui Cai, Department of Gastrointestinal Surgery, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China
Masahida Ikeguchi, the First Department of Surgery, Faculty of Medicine, Tottori University, Yonago 683-8504, Japan
Correspondence to: Jian-Hui Cai, Department of Gastrointestinal Surgery, the Second Hospital of Hebei Medical University, 215 Heping West Road, Shijiazhuang 050000, Hebei Province, China. jianhuicai@yahoo.com
Received: 2006-04-06Accepted: 2006-05-22
Abstract
AIM: To study the micrometastasis in the lymph nodes of mucosal gastric cancer.
METHODS: We examined 2526 lymph nodes from 84 patients with mucosal gastric cancer. Two consecutive sections were prepared, for simultaneous staining with hematoxylin and eosin and immunostaining with CAM 5.2 monoclonal antibody against cytokeratin (CK), respectively. A clinicopathological comparison was performed between patients with and without lymph node involvement.
RESULTS: Lymph node involvement was detected in 45 of 2526 (1.8%) lymph nodes. The incidence of nodal involvement was significantly increased, from 1.2% (1/84 patients) with hematoxylin and eosin staining, to 19% (16/84 patients) with CK immunostaining ......
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