胃肠道间质瘤的临床病理分析和免疫组化特点
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顾国利, 王石林, 任 力, 魏学明, 李德昌,
胃肠道间质瘤;临床病理;免疫组化,顾国利,王石林,魏学明,周晓武,黄蓉蓉,任力,李德昌,通讯作者:,电话:,收稿日期:,接受日期:,Histop
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顾国利, 王石林, 魏学明, 周晓武, 黄蓉蓉, 空军总医院普通外科 北京市 100036
任力, 李德昌, 空军总医院病理科 北京市 100036
通讯作者: 顾国利, 100036, 北京市海淀区阜成路30号, 空军总医院普通外科. kzggl@163.com
电话: 010-68410099-6302
收稿日期: 2006-06-15 接受日期: 2006-07-18
Histopathological and immunohistochemical features of gastrointestinal stromal tumors
Guo-Li Gu, Shi-Lin Wang, Li Ren, Xue-Ming Wei,De-Chang Li, Xiao-Wu Zhou, Rong-Rong Huang
Guo-Li Gu, Shi-Lin Wang, Xue-Ming Wei, Xiao-Wu Zhou, Rong-Rong Huang, Department of General Surgery, General Hospital of Chinese PLA Air Force, Beijing 100036, China
Li Ren, De-Chang Li, Department of Pathology, General Hospital of Chinese PLA Air Force, Beijing 100036, China
Correspondence to: Guo-Li Gu, Department of General Surgery, General Hospital of Chinese PLA Air Force, Beijing 100036, China. kzggl@163.com
Received: 2006-06-15 Accepted: 2006-07-18
AbstractAIM: To explore the histopathological and immunohistochemical features of gastrointesti-nal stromal tumors (GIST).
METHODS: Immunohistochemistry was performed in GIST, for a panel of antibodies such as CD117, CD34, Vim, SMA, S-100 by SP staining methods. Clinical data and follow-up documents of 24 patients with GIST admitted from January 2000 to May 2006 were studied retrospectively.
RESULTS: There were 24 patients (males and 8 females) aged from 29 to 75 (mean 54.5 ± 13.5). The tumors were mainly located at the stomach, small bowel and rectum. The initial presentations were bellyache (33.3%), abdomen mass (25.0%) and gastrointestinal bleeding (20.8%) in the most cases. All patients received successful surgical resection of tumor and the total resection rate was 100%. The rate of recurrence and metastasis was 14.3% (3/21) after operation. The most cases were diagnosed after surgical resection. Tumor size varied from 2 to 16 cm (mean 6.6 cm). The cells were spindle-like, and the epithelioid cells were rare ......
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