[摘要] 目的 探讨胎膜早破的病因及预防。方法 对1998～2005年住院胎膜早破1249例产妇资料进行回顾性分析，同期非胎膜早破8080例为对照组。对胎膜早破的原因进行分析，对发病组与对照组的剖宫产率、产褥病率、早产率、新生儿窒息率、新生儿肺炎率进行对比。结果 胎膜早破可能与感染、人工流产史、中期引产、头盆不称有关，胎膜早破的剖宫产率、产褥病率、早产率、新生儿窒息率、新生儿肺炎率均比对照组高(P<0.01)。结论 感染、人工流产史、中期引产史、头盆不称是胎膜早破的主要原因，应针对病因进行预防，减少母儿并发症。

    [关键词] 胎膜早破；早产；剖宫产术

    Analysis on the causes of 1249 cases of premature rupture of fetal membranes

    ZHANG Xiu-fen.Miyun Maternity and Child Care Hospital，Beijing 101500，China

    [Abstract] Objective To explore etiology and prevention of premature rupture of membrane (PROM).Methods Retrospective study was performed for the cases of 1249 women with PROM from 1998 to 2005 in our hospital ......