【摘要】 动脉粥样硬化是严重影响人类健康的疾病之一。它发生的机理被认为主要是由于膜受体CD36与低密度磷脂蛋白结合形成泡沫细胞沉积血管内壁所致，本文简要地对CD36的结构与功能，低密度蛋白特性和形成与动脉粥样硬化的关系进行了综述和讨论分析，为进一步深化对该疾病的发生机理和预防提供理论依据。

    【关键词】 CD36；oxLDL；动脉粥样硬化；膜受体

    CD36，oxLDL and atherosclerosis

    ZHANG Jian-she.

    Department of Bioengineering and Environmental Science, Changsha University, Changsha,Hunan 410003，China

    【Abstract】 Atherosclerosis is one of the serious diseases to human and it is mainly caused by the interaction of a scavenger gene family member, membrane receptor CD36 and lipoprotein, oxLDL to form foam cells in the sub-endothelial space of the involved vessel. In this article, the molecular characteristics and physiological functions of CD36 and oxLDL as well as their relation to the occurrence of atherosclerosis were briefly reviewed and analyzed. The information provides us to a better understanding of the mechanism of atherosclerosis and the pervention for the disease.

    【Key words】 CD36;oxLDL; atherosclerosis; receptor

    动脉粥样硬化(Atherosclerosis)是严重影响人类健康的疾病之一。近年来，随着心脑血管发病率逐年增高的趋势，对于动脉粥样硬化产生的机理已成为医学界和生物界广为研究的热门课题。综合已有研究成果证实 ......