乙肝表面抗原大蛋白与HBV DNA的比较及其与ALT的关系
http://www.100md.com
杨延敏, 王洪笑, 王桂利, 崔亚利, 梁 萍
乙肝病毒表面抗原大蛋白;HBVDNA;丙氨酸转氨酶,乙肝表面抗原大蛋白与HBVDNA的比较及其与ALT的关系,杨延敏,王洪笑,王桂利,崔亚利,梁萍,通讯作者:,Comparisonbetweenh
 |
| 第1页 |
参见附件(847KB，4页)。
杨延敏, 王洪笑, 王桂利, 崔亚利, 梁萍, 北京丰台医院 北京市 100071
通讯作者: 杨延敏, 100071, 北京市丰台区, 北京丰台医院检验科. yyanmin2005@yahoo.com.cn
收稿日期: 2006-07-13 接受日期: 2006-07-19
Comparison between hepatitis B virus large protein and DNA and its association with alanine aminotransferase level
Yan-Min Yang, Hong-Xiao Wang, Gui-Li Wang, Ya-Li Cui, Ping Liang
Yan-Min Yang, Hong-Xiao Wang, Gui-Li Wang, Ya-Li Cui, Ping Liang,Beijing Fengtai Hospital, Beijing 100071, China
Correspondence to:Yan-Min Yang, Department of Laboratory Medicine, Beijing Fengtai Hospital, Beijing 100071, China. yyanmin2005@yahoo.com.cn
Received:2006-07-13 Accepted:2006-07-19
Abstract
AIM: To explore the clinical significance of hepatitis B virus large protein (HBV-LP) in the diagnosis of viral replication.
METHODS: Serum samples were collected from 177 patients with HBV infection. HBV-LP, HBV preS1 and HBV markers were examined using enzyme linked immunosorbent assay (ELISA). HBV DNA was quantitatively detected by real-time polymerase chain reaction. The level of alanine aminotransferase was obtained by an automated biochemistry analyzer.
RESULTS: No significant difference was found between the detectable rates of HBV DNA and HBV-LP in patient with the same HBV markers. The positive rates of HBV-LP and HBV DNA in HBeAg-positive patients were higher than those of HBeAg negative ones (95.45% vs 44.36%, P < 0.05; 93.18% vs 41.35%, P < 0.05). There was significant difference between the detectable rates of HBV DNA and HBV preS1 in patients with the same HBV markers (P < 0 ......
您现在查看是摘要介绍页，详见PDF附件(847KB，4页)。