[摘要] 目的 探讨70岁以上高龄大肠癌的临床特点及外科治疗原则。方法 回顾性分析206例经手术和病理证实的70岁以上高龄大肠癌患者临床资料。结果 本组患者男97例，女109例，年龄70～91岁，平均77.2岁。肿瘤部位：结肠114例，直肠92例。组织病理学分类：管状及乳头状腺癌172例(83.5%)，黏液腺癌19例，印戒细胞癌11例，未分化癌7例。全组高、中分化腺癌154例，占74.8%。206例中Dukes分期A期8例(3.9%)，B期64例(31.1%)，C期102例(49.5%)，D期32例(15.5%)。所有患者均行手术治疗(33例因并发结直肠梗阻而行急症手术)，其中151例(73.3%)属根治性切除，41例姑息性切除，11例仅永久性结肠造口术，3例剖腹探查加肿瘤活检术。总切除率为94.2%。无手术死亡病例。获随访199例(96.6%)。总的2年和5年生存率分别为93.2%和53.6%。结论 对高龄大肠癌患者应采取个体化治疗方案，原则是尽可能行肿瘤根治性切除，预防或解除梗阻，以提高患者生活质量和生存率。

    [关键词] 结直肠肿瘤；老年人；治疗学

    Surgical therapy of colorectal cancer in the elderly

    ZHANG Lin-gen,LV Qiang,FENG Guo-guang,et al.Department of General Surgery,Gongli Hospital,Shanghai 200135,China

    [Abstract] Objective This study was designed to explore the clinical characteristics and principle of surgical treatment of large bowel cancer in the elderly.Methods The clinical data of 206 elderly patients with large bowel cancer resected by operation and confirmed by pathology were retrospectively analysed.Results There were 97 males and 109 females in all patients.The median age was 77.2 years (range,70~91).114 tumours located in colon,92 in rectum.Pathologic classification：duct and papilla adenocarcinoma 167 cases(81.1%) ......