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食管基底细胞样鳞癌的临床病理特点及预后分析
http://www.100md.com 《中华现代外科学杂志》 2006年第13期
食管癌;基底细胞样鳞癌,,],食管癌;基底细胞样鳞癌,1临床资料,2讨论,[参考文献]
     [摘要] 目的 探讨食管基底细胞样鳞癌(BSC)的临床病理及预后特点。方法 总结四川大学华西医院胸外科2000年7月~2003年5月行根治性切除手术的1257例食管癌患者,检出基底细胞样鳞癌18例,随机抽取同期手术的传统食管鳞癌患者54例,作为对照分析食管基底细胞样鳞癌(BSC)的临床病理及预后特点。结果 与传统食管鳞癌相比,基底细胞样鳞癌患者的平均发病年龄显著提高[(61.56±7.62)vs(56.11±10.58),P<0.05],T4患者比例明显增大(27.8% vs 5.6%,P<0.05)术后转移率显著增加,术后生存时间明显下降。结论 食管基底细胞样鳞癌术后转移能力可能高于传统鳞癌,术后更需综合治疗以提高生存时间。

    [关键词] 食管癌;基底细胞样鳞癌

    Clinicopathological characteristics and prognosis analysis of esophagus basaloid squamous carcinoma

    GAO Yu-yong,WANG Yun.Tianquan Peoples Hospital,Sichuan 622500,China

    [Abstract] Objective To investigate the clinicopathological features and prognostic aspect of basaloid squamous carcinoma (BSC).Methods We reviewed 1257 documented cases that underwent potentially curative resection, and discovered 18 (1.4%) cases of BSCs.The clinicopathological and prognostic parameters of these 18 BSCs and 54 typical SCCs of the esophagus were compared.Results The patients suffered with BSC is significantly older(61.56±7.62 vs 56.11±10.58,P<0.05), and the ratio of T4 stage is much higher(27.8% vs 5.6%,P<0.05) than those with typical SCC.The follow-up shows that, comparing with typical SCC, the ratio of metastasis is higher(62.5% vs 25%,P<0.05), and mean survival time is significantly shorter in patients with BSC after curative resection.Conclusion Both invasiveness and metastasis of BSC are more usual than those of typical SCC,and multiple therapy is necessary to this disease. ......

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