脑梗死；IL1;IL6_

急性脑梗死患者血清中IL1β及IL6水平变化的研究

http://www.100md.com 《河北北方学院学报》 2006年第2期

脑梗死；IL1;IL6,,脑梗死；IL1;IL6,1资料与方法,2结果,3讨论,参考文献

     【摘要】目的:研究急性脑梗死患者血清中IL1β及IL6含量的变化。方法：采用病例对照的研究方法，选择急性脑梗死患者45例为病例组，健康体检者40例为对照组，用酶联免疫吸附法定量检测血清中IL1β及IL6的含量。结果：病例组血清中IL1β、及IL6的含量平均值分别是248±51pg/ml和232±84pg/ml；对照组分别是150±46pg/ml和195±99，两组比较有统计学意义。结论：急性脑梗死患者血清中IL1β及IL6的含量明显增高，后者是导致急性脑梗死的发展机制之一。

    【关键词】脑梗死；IL1;IL6

    Study on the Changes of IL6 and IL1β Levels in the Serum of Acute Cerebral Infarction Patients

    YU Aimei, ZOU Yuan

    Department of Neurology, the First Affiliated Hospital,

    Hebei North University, Zhangjiakou, 075000, Hebei China

    【ABSTRACT】 Objective： To study the changes of IL6 and IL1β levels in the serum of acute cerebral infarction patients.Methods: By the casecontrol study, 45 cases with acute cerebral infarction (patients group) and 40 health controls (control group) were selected, then test IL6 with ELISA.Results:The average values of IL1β and IL6 were 248±51pg/ml and 232±84pg/ml in patient group; the average values of IL1β and IL6 were 150±46pg/ml and 177±91 pg/ml in control group. There was statistical difference between patient group and control group.Conclusion:The average values of IL1β and IL6 were higher in patient group than that of control group, and these elements might bring about acute cerebral infarction. ......

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