不同组织微环境中人胃癌异种移植瘤生物学行为及明胶酶的表达差异
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李玉莲, 耿敬姝
明胶酶;侵袭;原位杂交;肿瘤移植李玉莲,耿敬姝.不同组织微环境中人胃癌异种移植瘤生物学行为及明胶酶的表达差异. 世界华人消化杂志2006;14(32)3136-3138,不同组织微环境中人
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李玉莲, 耿敬姝, 哈尔滨医科大学附属肿瘤医院 黑龙江省哈尔滨市 150081黑龙江省自然科学基金资助项目, No.D2005-11
通讯作者: 李玉莲, 150081, 黑龙江省哈尔滨市南岗区哈平路150号, 哈尔滨医科大学附属肿瘤医院. liyulian1@yahoo.com.cn
电话: 0451-86298115 传真: 0451-86298116
收稿日期: 2006-09-12 接受日期: 2006-09-25
Diversified biological behaviors and gelatinase expression of human gastric carcinoma xenografts in different organic micro-environment
Yu-Lian Li, Jing-Shu Geng
Yu-Lian Li, Jing-Shu Geng, Tumor Hospital of Harbin Medical University, Harbin 150081, Heilongjiang Province, China
Supported by the Natural Science Foundation of Heilongjiang Province, No. D2005-11
Correspondence to: Yu-Lian Li, Tumor Hospital of Harbin Medical University, Harbin 150081, Heilongjiang Province, China. liyulian1@yahoo.com.cn
Received: 2006-09-12 Accepted: 2006-09-25
Abstract
AIM: To study the expression of gelatinase (matrix metalloproteinase, MMP) and its effect on the biological behaviors of human gastric carcinoma xenografts in different organic micro-environment.
METHODS:In situ hybridization was used to detect the mRNA expression of MMP-2 and MMP-9 in tumors transplanted subcutaneously and intraperitoneally ......
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