【摘要】 目的 了解γ射线辐照和保存期对单采血小板的影响。方法 单采血小板分为两组：一组25Gy剂量辐照，一组不辐照处理，作为对照组；在贮存的第0、5天分别检测单采血小板计数、pH和表达CD62P的特异性荧光结合阳性血小板百分率(%)。结果 保存过程中，辐照组血小板计数及pH值与对照组无显著差异(P>0.05)；5天的贮存可显著增加了血小板表达CD62P百分率(P<0.05)，但辐照组与对照组的血小板在贮存第5天时表达CD62P 百分率无显著差异(P>0.05)。结论 25Gy的辐照对血小板制品的质量无明显影响，与普通血小板制品相同，辐照单采血小板可保存5天。

    【关键词】 血小板 辐照 CD62P

    Influence of Gamma Irradiation and Storage on Apheresis Platelets

    Wang Mingyuan,et al.

    (Suzhou Red Cross Blood Center,Suzhou,Jiangsu 215006)

    【Abstract】 Objective To investigate the influence of irradiation and storage on apheresis platelets.Methods Apheresis platelets were divided into two groups: one was irradiated with 25Gy,and the other served as a control.Platelet counts,pH and platelet activation marker CD62 antigen were determined in paired samples on the day of collection (day 0) and after 5 days of storage (day 5).Results No significant differences in Platelet counts and PH between the irradiated and control platelets on day 0 or day 5.The 5-day storage significantly increased the percentages of CD62 percentages of CD62P staining was no significant differences in irradiated and control platelets on day 5(P>0.05).Conclusions Irradiation of 25Gy has not obviously influenced on the quality of apheresis platelets.The irradiated apheresis platelets can be kept for 5 days as ordinary apheresis platelets. ......