胃肠道间质瘤原发灶大小与预后的关系(附35例报告)
胃肠道；,间质瘤；,原发灶；,预后,,胃肠道；,间质瘤；,原发灶；,预后,1资料与方法,2结果,3讨论,参考文献:
摘要： 目的： 探讨胃肠道间质瘤(GIST)原发灶大小与预后的关系。方法： 对35例GIST临床资料进行回顾性分析。35例行完全手术切除，分析术后1、3、5年的生存率及肿瘤直径<5~10 cm和以肿瘤直径5 cm、10 cm为界的GIST患者的5年生存率。结果：术后复发转移8例，均死亡。术后1、3、5年生存率分别为97.12%、77.60%、67.26%。肿瘤直径<5 cm、5～10 cm与≥10 cm GIST患者5年生存率分别为93.80%、84.40%和28.00%(P<0.05),肿瘤直径﹤5 cm与≥5 cm GIST患者5年生存率分别为93.80%、54.31%(P<0.05),肿瘤直径<10 cm与≥10 cm GIST患者5年生存率分别为87.70%、28.00%(P<0.05)。结论： GIST完全切除后，肿瘤原发灶大小是影响预后的独立高危因素，肿瘤直径≥5 cm的患者术后应加强随诊。关键词： 胃肠道； 间质瘤； 原发灶； 预后
Prognostic significance of primary tumor size in gastrointestinal stromal tumor: report of 35 cases
WANG Haijiang， CHEN Bingxue， CHEN Peng
(Department of Abdominal Surgery, Affiliated Tumor Hospital, Xinjiang Medical University, Urumqi 830011, China)
Abstract: Objective: To analyze the prognostic significance of primary tumor size in gastrointestinal stromal tumors (GIST). Methods: The clinical data of 35 patients with GISTs were analyzed retrospectively. To study the overall survival rate at 1, 3and 5year and the survival of three groups divided by 5 cm, 10 cm, 5～10 cm at 5 year. Results: The 8 GISTs died of recurrence and metastasis. The overall survival rate at 1, 3 and 5 year were 97.12%, 77.60% and 67.26% respectively. The 5year survival rate for tumors <5 cm, 5～10 cm and ≥10 cm were 93.80%, 84.40% and 28.00% respectively (P<0.05). The 5year survival rate for tumors <5 cm and ≥5 cm were 93.80% and 54.31% (P<0.05). The 5year survival rate for tumors <10 cm and ≥10 cm were 87.70% and 28.00% (P<0.05). Conclusions: Tumor size was an independent prognostic factor in patients with GIST. Patients with tumor size more than 5 cm should be intensively followedup. ......
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