【摘要】 目的 观察氯胺酮复合利多卡因、咪唑安定、异丙酚用于小儿眼科手术不同年龄段的临床效果。方法 选200例各类眼科短小手术，年龄从1个月至9岁，体重5～30kg，男114例，女86例。ASA 1级，无先天性疾患。按年龄分为3组，A组：1个月到3岁共62例，用药为氯胺酮+利多卡因，B组：3～6岁共71例，用药为氯胺酮+咪唑安定，C组：6～9岁共67例，用药为氯胺酮+异丙酚，观察术中麻醉效果及各类并发症的发生率。结果与结论 3组术中各类并发症发生率无明显差异，说明氯胺酮与不同药物配伍应用于不同年龄段小儿眼科麻醉是安全有效的。

    【关键词】 氯胺酮； 小儿眼科； 复合麻醉

    Clinical investigation of general anesthesia using compound ketamine for ophthalmic operation of children

    CHENG Wen-cong,WANG Jia-he.

    Department of Anesthesiolog,Affiliated Beijing Tongren Hospital of Capital University of Medical Sciences,Beijing 100730,China

    【Abstract】 Objective To observe the clinical effect of ketamine combined with lidocaine, midazolam and propofol used in ophthalmic operation of children in different age groups. Methods 200 patients without any congenital diseases with ASA I status undergoing different short ophthalmic operation were divided into 3 groups by age. 114 boys and 86 girls, the weight is from 5kg to 30kg and the age is from 1 month to 9 years old .GroupA: 62 children from 1 month to 3 years use ketamine + lidocaine； GroupB: 71 children from 3 to 6 years use ketamine + midazolam；GroupC: 67 children from 6 to 9 years use ketamine + propofol, and observe the anesthetic effect and the rate of any subsequent syndrome. Results There is no significant difference of the rate of subsequent syndrome among 3 groups.Conclusion It indicates that ketamine with other drugs used in ophthalmic operation of different aged children is safe and effective. ......