Scrotal Cancer

http://www.100md.com 《新英格兰医药杂志》

     A 63-year-old man with generalized vitiligo presented with a two-year history of irritation and itching in his scrotal area. No ultraviolet treatment for the vitiligo had been received. Physical examination revealed an erythematous, raised lesion with an ulcerated center on the posterior aspect of the scrotum. This was initially treated as a fungal infection, but the irritation did not respond to antifungal therapy. Examination of a shave-biopsy specimen showed squamous-cell carcinoma. The patient underwent a partial scrotectomy, and pathological assessment showed invasive squamous-cell carcinoma with negative surgical margins. The results of tumor staging that was performed with the use of computed tomography were negative. The patient, a high-school sports coach, was disease-free at one year. Few etiologic factors for scrotal cancer have been determined, and there is no known relationship between scrotal cancer and vitiligo. Historically, scrotal cancer has been a disease of chimney sweeps.

    Thomas Schwaab, M.D., Ph.D.

    Ajay K. Nangia, M.D.

    Dartmouth–Hitchcock Medical Center

    Lebanon, NH 03756

    http://www.100md.com/html/DirDu/2007/01/01/32/52/77.htm