Adenocarcinoma of the Breast in a Man
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《新英格兰医药杂志》
An 83-year-old man presented with a one-month history of an enlarging lump on his right nipple. It was asymptomatic. Physical examination revealed an 11-mm erythematous, well-circumscribed nodule attached to the right nipple, which had begun to ulcerate in the center (Panel A), and a normal left nipple (Panel B). The nodule was excised with a 5-mm margin. Histologic examination showed an intraductal and invasive ductal adenocarcinoma of the breast, with the cancer invading the nipple from below. The patient underwent a complete mastectomy and axillary-node dissection. No residual carcinoma was found, and all lymph nodes were free of cancer, indicating a good prognosis. A delay in diagnosis is common in men with breast cancer because patients and physicians do not recognize the clinical features. Breast cancer affects more than 1600 men per year in the United States, and treatment is currently based on the same guidelines used for the treatment of breast cancer in women.
Andrew Birnie, M.R.C.P.
Sandeep Varma, M.R.C.P.
Queen's Medical Centre
Nottingham NG7 2UH, United Kingdom
Andrew Birnie, M.R.C.P.
Sandeep Varma, M.R.C.P.
Queen's Medical Centre
Nottingham NG7 2UH, United Kingdom