原发性小肠恶性间质瘤伴腹腔广泛转移1例并文献复习 (pdf)

    【摘要】 胃肠道间质瘤(gastrointestinal stromal tumor ,GIST)是1998年以后识别并命名的新实体瘤。目前病理学家普遍接受GIST无绝对良性的观点，提倡分为恶性及恶性潜能未定肿瘤[1]。GIST引起患者死亡的主要原因是广泛侵犯临近器官和经血管转移至肺、肝或其他脏器。本例小肠恶性间质瘤的特点在于它在小肠上的原发灶呈结节状，似乎为多个肿瘤结节融合而成，并广泛转移至腹膜、网膜、肠壁、肠系膜形成多发性瘤结节，其数量多达千枚。为了更好的认识该病，现予报道，并进行文献复习。

    【关键词】 胃肠道间质瘤；免疫组织化学；腹腔转移

    Primary small intestinal malignant stromal tumor accompanied with widely metastasis in peritoneum,a case report and review

    LI Qiu-yang,YUAN Xiao-bin,WANG Zi-zhen,et al.Department of Pathology,Beijing Dianli Hospital,Beijing 100073,China

    【Abstract】 Gastrointestinal stromal tumor(GIST) is recognized and named a new tumor after 1998.Now pathologists generally accept the idea that GIST is not absolutely benign and advocate GIST is classified into malignant and potenial malignant tumor.The main reason for death of GIST patients is widely invading nearby to lung,liver and other organs throuth vessels.The character of this small intestinal stromal tumor lines in its primary lesion is nodelike,just as many tumor nodes mixing together,and forming multiple tumor nodes in peritoneum,omentum,intestinal wall and intestinal mucosa by widely metastasis.The number of nodes can reach to several thousands.To recognize the disease better,the review and report are as follows. ......