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塑料刷取样涂片法应用于宫颈癌病变检测的研究
http://www.100md.com 《中华医学研究杂志》 2006年第12期
塑料刷取样;细胞学;宫颈癌;TBS诊断,,塑料刷取样;细胞学;宫颈癌;TBS诊断,1资料与方法,2结果,3讨论,【参考文献】
     塑料刷取样涂片法应用于宫颈癌病变检测的研究 (pdf)

    【摘要】 目的 探讨塑料刷取样涂片法在宫颈病变检测中的意义,以期找到宫颈癌早期筛查的合理方案。方法 2005年5~12月,对在徐州市第一人民医院妇产科门诊就诊的妇女分别以传统宫颈细胞涂片法(1850例),塑料刷取样涂片法(1500例),液基细胞检查(TCT)法(2200例)进行宫颈病变的检测。细胞诊断系用TBS分级系统,阳性诊断为意义不明的不典型鳞状上皮(ASCUS)及以上病变。所有阳性结果病例全部在阴道镜下活检。结果 传统宫颈细胞涂片法、塑料刷取样涂片法、TCT法对ASCUS以上病变的检出率分别为4.9%、9.8%、10.2%,后二者与前者相比,结果差异有显著性(P﹤0.01),后两者结果无明显差别(P﹥0.05)。三者与病理诊断的阳性符合率分别为20.8%、36.7%、35.8%,后两者与前者相比有明显优势(P﹤0.05),而后两者无明显差别(P﹥0.05)。结论 塑料刷取片法应用于宫颈病变的检测操作简单,费用较低,特异性敏感高,较传统涂片法及TCT有明显优势,可作为宫颈癌筛查的最佳选择。

    【关键词】 塑料刷取样;细胞学;宫颈癌;TBS诊断

    Study on test of early cervical cancer and precancer lesions by drawing materials and smearing with plastic brush

    CAO Zhen-lang, ZHANG Shu-xuan, LIU Yong-li, et al. Department of Obestetrics and Gynecology, Xuzhou First People ’s Hospital,Xuzhou 221002,China

    【Abstract】 Objective This study was designed to explore the best program of a diagnosis of cancer and early cervical precancer lesions. Methods 1850cases,1500 cases and 2200 cases in Xuzhou First People ’s Hospital, Jiangsu Province ,from May to December 2005 were tested for cervical lesions with traditional cervical smears ,drawing material and smearing cells with liquid based thinprep plastic brush ,thinprep liquid based cytology test (TCT) respectively. Cell diagnosis adopted TBS-group system, and positive diagnosis included above-ASCUS pathological changes. All the examinations of above-ASCUS pathological changes were examined with colposcope. Results The above-ASCUS pathological changes identified by traditional smears , drawing material and smearing with plastic brush , TCT were 4.9% 9.8%,10.2% respectively. There were obvious differences between the first method and the latter two methods(P<0.01). There was no obvious difference between latter two methods (P>0.05). The positive coincidence rate between traditional smears and pathological examination was 20.8%, lower than that of the latter two methods 36.7%,35.8% (P <0.05).But there was no obvious difference between latter two methods (P>0.05).Conclusion The method of drawing materials and smearing with plastic brush has apparent dominance in decting above-ASCUS pathological changes with high sensitivity and specialty and lower price. It is suitable for early screening cervical cancer. ......

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