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奥美拉唑联合莫沙必利治疗反流性食管炎
http://www.100md.com 《中华中西医杂志》 2000年第20期
奥美拉唑;莫沙必利;反流性食管炎,,奥美拉唑;莫沙必利;反流性食管炎,1资料与方法,2结果,3讨论,【参考文献】
     【摘要】 目的 观察奥美拉唑联合莫沙必利治疗反流性食管炎的疗效。方法 将58例患者随机分为观察组(30例)和对照组(28例),观察组:奥美拉唑20mg,每日2次,莫沙必利5mg,每日3次;对照组:法莫替丁20mg,每日2次,莫沙必利5mg,每日3次。于治疗后8周观察烧心、反酸、胸痛等症状疗效,并复查胃镜,观察镜下愈合率。 结果 观察组临床有效率100%,内镜下有效率96.7%;对照组临床有效率75%,内镜下有效率71.4%,两组比较差异有显著性。 结论 奥美拉唑联合莫沙必利治疗反流性食管炎比法莫替丁联合莫沙必利具有更好的疗效。

    【关键词】 奥美拉唑;莫沙必利;反流性食管炎

    Omeprazole combined with mosapride on reflux esophagitis

    BO Lin-hui.Department of lnternal Medicine,Tianjin Baodi Hospital, Tianjin 301800, China

    【Abstract】 Objective To study the efficacy of omeprazole and mosapride in treating reflux esophagitis. Methods 58 cases of digestive out-patient were diagnosed with reflux esophagitis(all by biopsy diagnosis). They were divided into two groups, 30cases in group A(observe group): 20mg of omeprazole bid, 5mg of mosapride tid were taken orally; 28cases in group B(control group): 20mg of famotidine bid, 5mg mosapride tid were taken orally. During the course 8weeks of treatment, assess the symptoms of sick, heartbum and retrosternal pain in both groups respectively, and recheck the endoscope findings at the end of 8weeks. Results The clinical curative rates were 100% in group A and 75% in group B, the efficient rates evaluation under endoscope were 96.7% ......

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