摘要:目的 观察冠心病和肺心病病人血清心脏标志物浓度的变化，探讨其在上述疾病中诊断和鉴别诊断的意义。 方法 将收治的冠心病人195例分为A组，肺心病病人79例分为B组;又将195例冠心病病人中前壁心肌梗塞80例分为C组，39例下壁心肌梗塞分为D组，76例心绞痛分为E组。分别测定其血清肌钙蛋白I(TnI)、肌红蛋白(MYO)、肌酸激酶-同工酶(CK-MB)浓度。 结果 肺心病病人少部分MYO、CK-MB轻度升高外，其余在参考值范围;冠心病例3种标志物有不同程度升高。两组经非参数检验(P<0.01)，有统计学意义。在冠心病病例中心肌梗塞组和心绞痛组的对比、心肌梗塞中前壁梗塞和下壁梗塞的对比，3种标志物升高程度不一，经配对非参数检验(P<0.01)，皆有统计学意义。 结论 3种标志物检测对于冠心病的诊断、分型、危险分层和治疗及与肺心病的鉴别诊断有重要意义。

    关键词:冠状动脉粥样硬化性心脏病;肺源性心脏病;生化标志物

    The significance of detecting the heart markers for diagnosis and differential diagnosis of coronary atherosclerotic heart disease and pulmonary heart disease.

    ZHENG Hui，OU Er-hong，LEI Ze-hong，et al.

    (Jiangmen Municipal Central People's Hospital，Jiangmen529000，Guangdong，P.R.China)

    Abstract:Objective To investigate the significance of detecting serum heart markers in patients with coronary atherosclerotic heart disease and pulmonary heart disease. Methods There were totally274patients divided into Group A consisted of195pa-tients with coronary heart disease and Group B consisted of79patients with pulmonary heart disease.While the195cases in Group A were again divided into Group C consisted of80patients with forward wall myocardial infarction ......