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A Medical Mystery — Extensive Ecchymosis
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     A 71-year-old man was evaluated for severe anemia (hemoglobin level, 7.1 g per deciliter; mean corpuscular volume, 106 μm3), extensive ecchymosis of the lower limbs (Panel A), gingivitis, and hemorrhages of the oral cavity (Panel B, arrows). There was no history of recent trauma. What is the diagnosis?

    Editor's note: We invite our readers to submit their answers at www.nejm.org/mystery. We will publish the diagnosis in the Correspondence section of the January 26, 2006, issue and e-mail it to everyone who submits an answer. All answers must be received by December 15, 2005.

    Denis Mulleman, M.D.

    Philippe Goupille, M.D.

    Fran?ois Rabelais University

    37032 Tours CEDEX 1, France