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EDITORIAL
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     The 2004 Database Issue of Nucleic Acids Research is the eleventh in a series dedicated to factual biological databases. Such databases are an essential resource for working biologists and this compilation provides descriptions of the most important of these databases and serves to introduce newly compiled databases that provide specialist information in the biological area. Editorial responsibilities for the entire Database Issue have been taken over by Dr Alex Bateman from Dr Andy Baxevanis.

    For several years, Andy Baxevanis has been producing a compendium of databases that includes all those databases described in Nucleic Acids Research, as well as selected other databases relevant to biologists. NAR Online contains hotlinks to all of the databases in the compilation as well as brief summaries of their content. Hotlinks are provided from that website directly to the homepage of each of the databases featured. Dr Baxevanis has now stepped down from this role and Michael Galperin from the NCBI has taken over responsibility for the Molecular Biology Database Collection. Individuals who wish to have their database listed in the Molecular Biology Database Collection or update a previous submission to the collection should contact Dr Michael Galperin directly (galperin@ncbi.nlm.nih.gov).

    The Executive Editors of Nucleic Acids Research are strongly in support of the principles of open access. At a recent meeting of the Editorial Board it was decided to move towards making Nucleic Acids Research an open access journal with all electronic content freely available to all. After consultations with our authors we have decided to use the Database Issue to investigate open access through author charges. More information about Nucleic Acids Research’s open access policy can be found at the following URL: http://www3.oup.co.uk/nar/openaccess.

    The Database Issue is open to submissions from commercial databases that are not freely available. These articles will undergo exactly the same peer-review process as normal articles but the commercial databases will have paid commercial rates instead of the usual author charge. These articles will be marked as such in the Acknowledgements section.

    Authors wishing to submit articles for the 2005 Database Issue, who have not previously contributed to a database issue, should be certain to contact Dr A. Bateman (nardatabase@mrc-lmb.cam.ac.uk) during the year, and no later than July 1, 2004. All new articles will need to be received by August 15, 2004 at the latest, and should be prepared according to the instructions on the Nucleic Acids Research website (http://nar.oupjournals.org/). Authors who are invited to submit articles providing updated information on databases that have previously been featured in Nucleic Acids Research should note that the deadline for submission of those articles is September 15, 2004.

    The Database Issue is the culmination of a huge amount of work by a large number of people. I would particularly like to thank Alice Ellingham and Gill Smith for excellent editorial assistance, Rich Roberts and Andy Baxevanis for helpful ideas and advice. Finally I would like to thank Claire Saxby, Kate Welsby and the rest of the team at Oxford University Press for producing the finished product.(EDITORIAL)