毛脉酸模；_大黄素；_大黄酚；_时空分布_

毛脉酸模根部大黄素和大黄酚含量的时空分布规律

http://www.100md.com 《时珍国医国药》 2006年第8期

毛脉酸模；,大黄素；,大黄酚；,时空分布,,毛脉酸模；,大黄素；,大黄酚；,时空分布,1仪器与材料,2方法,3结果,4讨论,参考文献：

     摘要：目的研究毛脉酸模根茎、根头部、根中部、根尖部、剩余根的大黄素和大黄酚含量的时空分布规律。方法采用高效液相色谱法，测定其根中各个部位的大黄素和大黄酚的含量。结果该植物中的两种生物活性成分表现明显的季节变化，大黄素的含量波动范围为0.01%～0.3%，而大黄酚含量在0.05%～0.9%之间变化。但它们在空间上无显著差异。结论该研究为寻找毛脉酸模的最佳采收期及最佳药用部位提供了理论依据和实践指导。

    关键词：毛脉酸模；大黄素；大黄酚；时空分布

    Space-time Distribution Pattern of Emodin and Chrysophanol Content in Root of Rumex gmelini

    YUE Yunfei, WANG Zhen-yue*,WANG Qianbo, LI Ruiming, WANG Zongquan, WANG Jing

    (Heilongjiang Province Institute for Drug Control ,Harbin 150001，China; College of Pharmacy , Heilongjiang University of TCM , Harbin 150040 , China; Chinese Medical Center, Tasly R&D Institute Tianjin 300402,China)

    Abstract：ObjectiveThe paper deals with spacetime distribution pattern of emodin and chrysophanol content in rhizome, root head, root central, root tip, surplus root in Rumex gmelini. MethodsThe content of emodin and chrysophanol in the parts of root were determined by HPLC. ResultsThe two active constituents have changed obviously with different seasons. The extent of the content of emodin was from 0.01% to 0.3%.The extent of the content of chrysophanol was from 0.05% to 0.9%. But their spatial contents little effect.ConclusionThe study supplied basis of theory and direction of practice for searching the date of gathering and the parts of herb plant. ......

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