Management of catecholamine substitution therapy in perioperation of pheochromocytoma (report of 15 cases)

    Chen Bin, Zhou Zhongquan, Xing Jinchun, Chen Shixin, Liu Rongfu, Wang Huiqiang, Zhang Kaiyan

    (Department of Urology, the First Hospital of Xiamen Affiliated of Fujian Medical University, Xiamen 361003, China)

    ABSTRACT: Objective To probe into the application of catecholamine substitution therapy in perioperation of pheochromocytoma. Methods 15 cases of pheochromocytoma were reviewed. All cases received a catecholamine substitution therapy in operation and postª²operation, without preoperative hydration. Results In all the 15 cases, an average of 2950mL fluid was given during surgery, and 400mL blood was transfused. 2500-3200mL fluid was given intravenously after surgery daily with no diet, and 500-1500mL fluid was given after diet. The blood pressure of 9 cases returned normal postª²operatively, that of 5 cases was controlled to normal level under hypotensor treatment, and that of 1 case remained unstable with hypotensor. Conclusion The management of catecholamine substitution therapy in perioperation to replace preoperative hydration can save time for some critical cases, and allow them more opportunities of surgery. It also reduces the cardiopulmonary complications due to the great amount of transfusion perioperatively. In this way, we can improve the success and safety of operation and relieve the economic burden on patients. ......