普外科病房深部念珠菌感染标本73例分析
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狄建忠, 张 频, 蒋燕群, 郑 起, 汪 昱, 冯昌宁
深部真菌感染;念珠菌;普外科,狄建忠,张频,蒋燕群,郑起,汪昱,冯昌宁,上海交通大学附属第六人民医院普外科上海市200233,蒋燕群,上海交通大学附属第六人民医院检验科上海市200233,通讯作者:张频,200233,上海市,上海交通大学附属第六人民医院普外科
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狄建忠, 张频, 蒋燕群, 郑起, 汪昱, 冯昌宁, 上海交通大学附属第六人民医院普外科 上海市 200233
蒋燕群, 上海交通大学附属第六人民医院检验科 上海市 200233
通讯作者: 张频, 200233, 上海市, 上海交通大学附属第六人民医院普外科. yzonnezp@126.com
电话: 021-64369181-1454
收稿日期: 2006-12-25 接受日期: 2007-01-10
Anaiysis of 73 specimens with deep candida infection in general surgical ward
Jian-Zhong Di, Pin Zhang, Yan-Qun Jiang, Qi Zheng, Yu Wang, Chang-Ning Feng
Jian-Zhong Di, Pin Zhang, Yan-Qun Jiang, Qi Zheng, Yu Wang, Chang-Ning Feng,Department of General Surgery, the Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200233, China
Yan-Qun Jiang,Department of Clinical Laboratory, the Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200233, China
Correspondence to:Pin Zhang, Department of General Surgery, the Sixth People’s Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China. yzonnezp@126.com
Received:2006-12-25 Accepted:2007-01-10
Abstract
AIM: To investigate the risk factors and prevention methods of deep fungal infection in general surgical ward.
METHODS: The clinical materials of 73 patients infected with nosocomial candida from January 2004 to December 2005 were retrospectively analyzed.
RESULTS: One hundred and twenty-two strains of candida were cultivated from in 73 specimens, and the infection rate of candida albicans was as high as 45% (55/122). The infection of candida glabrata and tropicalis covered a percentage of 40% (49/122) and 7% (8/122), respectively. The 5 patients with the highest infection rates were found with gastrointestinal carcinoma, severe acute pancreatitis, non-traumatic gastrointestinal perforation, hepatobiliary and pancreatic carcinoma, and abdominal trauma combined intestinal perforation. The patients with the mortality rate ranked the first four were diagnosed with non-traumatic gastrointestinal perforation, gastrointestinal carcinoma, acute obstructive cholangitis and severe acute pancreatitis. Eighteen of 73 cases died, and the mortality rate was 25%. Except for breast cancer, the mortality of the other diseases combined with fungal infection was obviously higher than that of the single diseases.
CONCLUSION: Gastrointestinal operations, gastrointestinal leakage, gastrointestinal fungal parasitism, broad-spectrum antibiotic usage, and senility are the important reasons for the secondary fungal infection in general surgical patients; timely and reasonable gastrointestinal operations, avoiding gastrointestinal leakage, non-bacterial operations, and gut barrier protection are significant measures to prevent deep fungal infection in general surgical ward.
Key Words: Deep fungal infection; Candida; General surgery
Di JZ, Zhang P, Jiang YQ, Zheng Q, Wang Y, Feng CN. Anaiysis of 73 specimens with deep candida infection in general surgical ward. Shijie Huaren Xiaohua Zazhi 2007;15(7):781-784 ......
狄建忠, 张频, 蒋燕群, 郑起, 汪昱, 冯昌宁, 上海交通大学附属第六人民医院普外科 上海市 200233
蒋燕群, 上海交通大学附属第六人民医院检验科 上海市 200233
通讯作者: 张频, 200233, 上海市, 上海交通大学附属第六人民医院普外科. yzonnezp@126.com
电话: 021-64369181-1454
收稿日期: 2006-12-25 接受日期: 2007-01-10
Anaiysis of 73 specimens with deep candida infection in general surgical ward
Jian-Zhong Di, Pin Zhang, Yan-Qun Jiang, Qi Zheng, Yu Wang, Chang-Ning Feng
Jian-Zhong Di, Pin Zhang, Yan-Qun Jiang, Qi Zheng, Yu Wang, Chang-Ning Feng,Department of General Surgery, the Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200233, China
Yan-Qun Jiang,Department of Clinical Laboratory, the Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200233, China
Correspondence to:Pin Zhang, Department of General Surgery, the Sixth People’s Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China. yzonnezp@126.com
Received:2006-12-25 Accepted:2007-01-10
Abstract
AIM: To investigate the risk factors and prevention methods of deep fungal infection in general surgical ward.
METHODS: The clinical materials of 73 patients infected with nosocomial candida from January 2004 to December 2005 were retrospectively analyzed.
RESULTS: One hundred and twenty-two strains of candida were cultivated from in 73 specimens, and the infection rate of candida albicans was as high as 45% (55/122). The infection of candida glabrata and tropicalis covered a percentage of 40% (49/122) and 7% (8/122), respectively. The 5 patients with the highest infection rates were found with gastrointestinal carcinoma, severe acute pancreatitis, non-traumatic gastrointestinal perforation, hepatobiliary and pancreatic carcinoma, and abdominal trauma combined intestinal perforation. The patients with the mortality rate ranked the first four were diagnosed with non-traumatic gastrointestinal perforation, gastrointestinal carcinoma, acute obstructive cholangitis and severe acute pancreatitis. Eighteen of 73 cases died, and the mortality rate was 25%. Except for breast cancer, the mortality of the other diseases combined with fungal infection was obviously higher than that of the single diseases.
CONCLUSION: Gastrointestinal operations, gastrointestinal leakage, gastrointestinal fungal parasitism, broad-spectrum antibiotic usage, and senility are the important reasons for the secondary fungal infection in general surgical patients; timely and reasonable gastrointestinal operations, avoiding gastrointestinal leakage, non-bacterial operations, and gut barrier protection are significant measures to prevent deep fungal infection in general surgical ward.
Key Words: Deep fungal infection; Candida; General surgery
Di JZ, Zhang P, Jiang YQ, Zheng Q, Wang Y, Feng CN. Anaiysis of 73 specimens with deep candida infection in general surgical ward. Shijie Huaren Xiaohua Zazhi 2007;15(7):781-784 ......
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