[摘要] 目的：探讨外伤性和血管性颅内出血患者心肌酶谱值变化对病情严重程度的影响及其与出血性质的关系 方法：选择外伤性和血管性颅内出血患者各40例分两组，入院时行GCS评分3-8分、9-15分重新分两组，入院24小时内测定血清AST、CK、CKMB、LDH，同期健康体检者40例为对照组。将测定值分别进行对比分析。结果：外伤性和血管性颅内出血患者血清心肌酶值均高于对照组有统计学意义；外伤性与血管性颅内出血患者血清心肌酶值升高对比无统计学意义；GCS3-8分组、GCS9-15分组与对照组两两对比均有统计学意义。结论：外伤性和血管性颅内出血患者急性期血清心肌酶谱值的升高程度与出血性质无明显相关性，而与病情严重程度相关，可作为判断预后的指标之一。

    关键词：外伤性颅内出血；血管性颅内出血；心肌酶谱

    [Abstract] Objective To explore the change of cardiac muscle zymogram in traumatic and vascular intracranial hemorrhage petients between the effection on sererity trauma of injury status and the relationship of characteristic of hemorrhage.Methods Each 40 cases of traumatic and vascular intracranial hemorrhage petients were selected divided into two groups. According to admission GCS grade3-8′and 9-15′were reclassificated two groups, determinating blood gerum of AST 、CK、CKMB、LDH during the first 24h, and 40 cases of healthy physical examination were divided into control group at the same period. Comparing the estimated value Results The blood cardiac muscle zymogram of traumatic and vascular intracranial hemorrhage petients was above control group had statistics signification; the blood cardiac muscle zymogram of traumatic and vascular intracranial hemorrhage petients above normal was contrast had no statistics signification; GCS 3-8′group ,GCS 9-15 ′group and control group were contrast each other had statistics signification Conclusion Traumatic and vascular intracranial hemorrhage patient's blood cardiac muscle zymogram is high in acute phase, and the degree has unrelated to characteristic of hemorrhage, but has related to sererity trauma of injury status,directly effect prognosis. ......