【摘要】 目的 探讨CYFRA21-1、CEA、CA199联合检测对消化道恶性肿瘤的诊断价值。方法 对消化道恶性肿瘤患者138例和非肿瘤对照者60例进行CYFRA21-1、CFA、CA199三项肿瘤标志物联合检测。结果 联合检测三种肿瘤标志物在恶性消化道肿瘤组出现一项及一项以上阳性率明显高于对照组。结论 联合检测三种肿瘤标志物有助于提高诊断的阳性率，对消化道恶性肿瘤的诊断具有临床实用价值。

    【关键词】 CYFRA21-1； CEA； CA199；消化道恶性肿瘤

    Diagnosis values of combined detected of serum CYFRA21-1，CEA and CA199 in alimentary canal malignancy

    TU Zhi-quan,ZHANG Ding-chang.The Eighth People’s Hospital of Shanghai，Shanghai 200235,China

    【Abstract】 Objective To evaluate the diagnosis value of combined determination of serum CYFRA21-1，CEA and CA199 in the patients with alimentary canal malignancy.Methods Combined detected of serum CYFRA21-1，CEA and CA199 in 138 patients with alimentary canal malignancy and 60 healthy subjects.The positive of the serum markers were evaluated.Results The positive result of one or more serum markers were higher in the patients with malignancy than control subjects.Conclusion Combined detected of serum CYFRA21-1 ......