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鼻咽癌放射治疗后鼻腔粘连防治探讨
http://www.100md.com 《癌症》1999年第4期
鼻咽肿瘤|放射疗法|鼻腔粘连
     作者:周永 唐安洲 李杰恩 曾钢 兰新海

    单位:广西医科大学一附院耳鼻喉科(南宁,530027)

    关键词:鼻咽肿瘤;放射疗法;鼻腔粘连

    癌症990426

    【摘要】目的:研究鼻咽癌放疗后鼻腔粘连的发病情况及其影响因素和治疗方法。方法:临床治疗28例鼻咽癌放疗后鼻腔粘连病例,并随机抽取123例鼻咽癌放疗后患者的鼻咽轴位CT,统计鼻腔粘连的发病情况。结果:CT资料显示鼻腔粘连发生率为28.5%,其中94%的病人发生在放疗后6个月内,女性、接受鼻咽腔内照射以及放疗前鼻咽肿瘤浸润程度广泛的病人,容易发生鼻腔粘连。经治疗后的鼻腔粘连病例,鼻腔再通气效果良好。结论:鼻咽癌放疗后的鼻腔粘连有较高的发生率,多于放疗后6个月内形成;它与性别、鼻咽腔内照射、鼻咽肿瘤的浸润程度等有密切的关系;鼻内窥镜手术是治疗鼻腔粘连的最佳方法。

    中图分类号:R739.63 文献标识码:A 文章编号:1000-467X(1999)04-0440-03

    Nasal adhesion after radiotherapy in the patients with nasopharyngeal carcinoma

    ZHOU Yong, TANG An-zhou, LI Jie-en,et al.

    Department of Otolaryngology,First Affiliated Hospital,Guangxi Medical University,Nanning 530027, P.R.China

    【Abstract】 Objectives:To study the incidence,affecting factors and treatment apporach of nasal adhesion after radiotherapy in the patients with nasopharyngeal carcinoma (NPC). Methods:Twenty-eight cases with nasal adhesion after radiotherapy were treated by operation through palate or endoscopic surgery.In the other group,the CT scanning of 123 patients with NPC before and after radiotherpay was observed and the incidence of nasal adhesion after radiotherapy was analyzed.Results:CT scanning group showed that the incidence of nasal adhesion was 28.5% ,and nasal adhesion were formed within 6 months after radiotherapy in 94% patients.Among these patients,in females,with nasopharynx received intracavitary irradiation and their nasopharygeal tumor infiltrated extensively were easier to develop nasal adhesions. By removing adhesive tissue,nasal ventilation in the most patients was recovered.Conclusions:Nasal adhesion is a common complication after radiotherapy in patients with NPC.The formation of nasal adhesion is within 6 months in the most patients and relates to female, nasopharyngeal intracavitary irradiation, and extensiveness of nasopharyngeal tumor infiltration.Endoscopic surgery is the best way to treat nasal adhesion. ......

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