大学生运动与非酒精性脂肪肝相关性分析(1)
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【摘要】 目的 探讨大学生运动与非酒精性脂肪肝的相关性,为预防非酒精性脂肪肝(NAFLD)的发生提供依据。方法 选取秦皇岛市425名在校大学生,根据运动情况分为A组(每周锻炼 4～7 d)、B组(每周锻炼1～3 d)和C组(不参加体育锻炼)。测量身高、体重、腰围(WC)和血压,检测空腹血糖(FPG)、血三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、谷丙转氨酶(ALT)、谷草转氨酶(AST)和血清真胰岛素(TI)水平,计算胰岛素抵抗指数(HOMA-IR),并行肝脏超声检查。结果 C组BMI,WC,TI和HOMA-IR水平高于A组和B组,C组HDL-C水平低于B组(P<0.05)。3组间比较,C组代谢综合征和NAFLD检出率明显升高(P<0.05)。Logistic回归分析显示,不参加体育锻炼是大学生代谢综合征的独立危险因素(OR=5.807,P=0.015);腹型肥胖(OR=7.476,P=0.000)和不参加体育锻炼(OR=2.614,P=0.031)是大学生NAFLD的独立危险因素。结论 不参加体育锻炼是大学生非酒精性脂肪肝和代谢综合征的独立危险因素。应早期指导大学生合理运动,预防非酒精性脂肪肝和代谢综合征的发生。
【关键词】 脂肪肝;运动活动;患病率;对比研究;学生
【中图分类号】 R 575.5 G 806 【文献标识码】 A 【文章编号】 1000-9817(2010)09-1088-03
Analysis on the Relationship of Exercise and Nonalcoholic Fatty Liver Diseases in College Students/HAN Gai-ling*, LU Qiang, XIE Chang-shun, et al.* Department of Endocrinology, the First Hospital of Qinhuangdao, Qinhuangdao(066000), Hebei Province, China
【Abstract】 Objective To determine the relationship between exercise and nonalcoholic fatty liver diseases(NAFLD) of the college students, and to provide evidence for the prevention. Methods 425 subjects (216 men and 209 women) were recruited from colleges of Qinhuangdao city. According to exercise, they were divided into A group (exercise 4-7 days per week), B group (exercise 1-3 days per week) and C group (not to participate in physical exercise). Anthropometric measurements, including height, weight, waist circumference and blood pressure. Fasting plasma glucose, serum lipids, true insulin and aminotransferase were assayed, and liver B-ultrasonic inspection were done. Results The BMI, WC, TI, and HOMA-IR of C group were higher than A group and B group, the HDL-C of C group levels was lower than B group(P<0.05). The detection rate of metabolic syndrome(MS) and NAFLD among the three groups were different. The detection rate of MS and NAFLD of C group was significantly higher(P<0.05) ......
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