综上所述，谵妄的发生是多因素引起的,虽然谵妄患者的预后不良并不能单纯归因于谵妄本身,但应高度重视引起术后谵妄的相关因素，并进行预防，减少术后谵妄的发生,改善患者的预后。

    参考文献

    [1] O’Keeffe ST ,Ni Chonchubhair A. Postoperative delirium in the elderly. Br J Anaesth ,1994 ,73 :673-687.

    [2]Inouye SK. Delirium in older persons. New Eng JMed, 2006, 354:1157-1165.

    [3]Marcantonio ER, Goldman L,Mangione CM, et al.A clinical p redictionrule for delirium after elective noncardiac surgery〔J〕.JAMA, 1994; 271(2) : 134-9.

    [4]谢荣.麻醉学〔M〕.北京:科学出版社, 1994: 442-4.

    [5]马长松,马春野.老年人术后谵妄分析〔J〕.中国老年病学杂志,1999; 19 (2) : 72.

    [6]Chisholm SE,Deniston OL, Igrisan R.Prevalence of confusion in postoperative patients〔J〕.J Geront Nursing, 2003; 18 (9) : 187-96.

    [7]Hibberd C ,Yau JL , Seckl J R . Glucocorticoids and t he ageinghippocampus. J Anat ,2000 ,197 :553-562.

    [8]阮 静,皋 源,杭燕南.全麻后中枢神经系统并发症〔J〕.中国医药导刊, 2007; 9 (5) : 387-90.

    [9]Gleason OC. Delirium. Am Fam Physician , 2003 , 67 : 10272-1034.

    [10]刘金虎 ......