大剂量甘草酸二铵治疗顽固性转氨酶异常的慢性肝炎疗效观察
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【摘要】目的：观察大剂量甘草酸二铵治疗以顽固性转氨酶异常为主的慢性肝炎的疗效。方法：80例慢性肝炎病人随机分成二组，在基础治疗之上对照组应用甘草酸二铵250mg/d，治疗组应用甘草酸二铵500mg/d，疗程4周。 结果：治疗后对二组患者的谷丙转氨酶水平和复常率恢复情况进行比较，治疗组的谷丙转氨酶较对照组有明显下降，差异有显著意义(t＝7.98， P<0.001)。复常率也显著高于对照组(X2 ＝16.97，P<0.001)。 结论：大剂量甘草酸二铵对以顽固性转氨酶异常为主的慢性肝炎有较好的疗效。
【关键词】甘草酸二铵；慢性肝炎
High-dose treatment of diammonium glycyrrhizinate aminotransferase abnormalities intractable chronic hepatitis
DONG Feng
【Abstract】 Objective: To observe the high-dose treatment of diammonium glycyrrhizinate to abnormal aminotransferase intractable chronic hepatitis mainly of the effect. Methods: 80 cases of chronic hepatitis patients were randomly divided into two groups, in the control group on the basis of the treatment of diammonium glycyrrhizinate 250 mg / d, the treatment group of diammonium glycyrrhizinate 500 mg / d, course of four weeks. Results: Group 2 after treatment of patients with ALT levels and normalization rate recovery to compare the treatment group of GPT than the control group decreased significantly, the difference was significant (t = 7.98, p <0.001). Normalization rate also increased significantly (X 2 = 16.97, P <0.001). Conclusion: The large dose of diammonium glycyrrhizinate to abnormal aminotransferase intractable chronic hepatitis mainly of a better effect. ......
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