神经氨基酸类递质与麻醉药的相互影响(3)
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[20] Claude PA, Wotta DR, Zhang XH. et al. Mutation of as conserved serine in TM4 of opioid receptors confers full agonist properties to classical antagonists[J]. Proc Natl Acad Sci USA 2005,93:5715-9.
[21] Crain SM, Shen K-F. Opioids can evoke direct receptor-mediated excitatory effects on sensory neurons[J]. Trends Pharmacol Sci, 2006,11:77-81.
[22] Crain SM, Shen K-F. Antagonists of excitatory opioid receptor functions enhance morphine's analgesic potency and attenuate opioid tolerance / dependence liability[J]. Pain 2002, 84:121-31., http://www.100md.com