比索洛尔和美托洛尔对甲亢性心动过速的疗效评价(1)
 |
| 第1页 |
参见附件。
【摘要】 目的:观察比索洛尔和美托洛尔对治疗甲亢性心动过速的疗效。方法:将确诊为甲亢性心动过速90例患者分为两组,比索洛尔组和美托洛尔组,比索洛尔组55例,观察患者在其治疗4周后的心率变化,同时随机抽取其中30例患者,观察患者在其治疗1周后的心率变化;美托洛尔组35例,观察患者在其治疗4周后的心率变化,同时随机抽取其中21例患者,观察患者在其治疗1周后的心率变化,两组药物均在甲状腺基础用药上应用。最后评定两组在1周和4周后的疗效。结果:比索洛尔组和美托洛尔组在1周和4周后对控制甲亢性心动过速的显效率和总有效率无统计学差异,(P>0.05)。结论:比索洛尔和美托洛尔对甲亢性心动过速的疗效相当。
【关键词】甲亢性心动过速;比索洛尔;美托洛尔
Bisoprolol and metoprolol on the efficacy evaluation of hyperthyroid tachycardia
Fengcai Lian Jiang NingYi Sun Yunfeng Shi LiHong Jiang Song
【Abstract】 Objective: To observe the effect of bisoprolol and metoprolol on the efficacy of treatment of hyperthyroid tachycardia. Methods: The diagnosis of thyrotoxic tachycardia 90 cases were divided into two groups, bisoprolol group and metoprolol group, bisoprolol group of 55 cases observed in patients in their treatment for 4 weeks after the heart rate changes, while random sampling in which 30 patients were observed in patients treated 1 week after their heart rate changes; metoprolol group of 35 cases were observed in patients in their treatment for 4 weeks after the heart rate changes, while 21 patients were randomly selected in which to observe the patients in their treatment of 1 week after the heart rate changes, the basis of two groups of drugs are in the thyroid medication to apply. Final assessment of the two groups at 1 week and 4 weeks after the effect. Results: The effect of bisoprolol group and metoprolol group at 1 week and 4 weeks after control of hyperthyroid tachycardia significant efficiency and total efficiency is not statistically significant difference, (P> 0.05). Conclusion: The effect of bisoprolol and metoprolol on the efficacy of hyperthyroid tachycardia fairly.
【Key words】 Thyrotoxic tachycardia ;bisoprolol;metoprolol
【中图分类号】R762【文献标识码】A【文章编号】1005-0515(2010)010-0021-02
甲状腺功能亢进(简称甲亢)是由于甲状腺或甲状腺以外的多种原因引起的甲状腺激素增多,进入循环血中,作用于全身的组织和器官,造成机体的神经,循环,消化等系统的兴奋性增高和代谢亢进为表现的疾病。而甲亢对机体心血管系统影响十分突出,据资料显示[1],甲亢患者心动过速的发生率约达82%,查体时,甲亢患者大陪分会出现心动过速的体征.。由于心动过速,导致心排出量增加,血循环加速,外周血管扩张等高动力循环状态,患者常诉心悸,胸闷,气促等不适,活动后更加明显。长期的心动过速不仅严重影响患者的生活质量,而长期严重的心动过速会导致心脏扩大,心律失常,心绞痛,心肌梗死,充血性心力衰竭等。为此,我科于2009年10月至2010年4月对随机抽取的甲亢性心动过速患者进行给予比索洛尔和美托洛尔缓释片治疗,观察两者对甲亢性心动过速的疗效,报告如下: ......
您现在查看是摘要介绍页，详见PDF附件(1517kb)。