【摘要】目的：探讨呼吸机相关肺炎(VAP)的致病菌群和治疗方法。方法：分析84例VAP临床资料及呼吸道分泌物细菌培养的结果及治疗转归。结果：VAP发生率为48.8%，病原菌以革兰氏阴性菌为主，占菌株总数71.3%，主要为假单胞菌属、不动杆菌属、肠杆菌属及金黄色葡萄球菌是VAP的主要致病菌。降阶梯疗法的患者死亡率较低。结论：应重视对VAP的病原学监测，指导降阶梯治疗的抉择，以提高临床诊断与治疗水平。

    【关键词】

    Distribution of Pathogens and Treatnent Patterns in Patients with Ventilator-Associated Pneumonia

    Zhao Shan Zhang Yunhui Yuan Bing

    【Abstract】ObjectiveTo analyse pathogens and treatment matters in ventilator-associated pneumonia(VAP).Methods We analysed the pathogen of respiratory tract secretion and outcomes of 84 cases of VAP patients. Results The incidence of VAP was 48.8%. Gram-negative bactilli(GNB) were the main pathogen in VAP . Among the strains of pathogen collected,the GNB occupied 71.3%. Among the VAP, Pseudomonas,Acinetobacter,Enterobacter and Straphylococcus aureus. Were the main pathogens. The mortality rate was significantly lower among patients in whom theraphy was deescalated. ConclusionsTo improve the clinical diagnosis and treatment, the pathogen monitoring of VAP patients should be paid more attention. ......