脑电双频谱指数指导下的临床麻醉深度研究(1)
摘 要：目的 研究脑电双频谱指数指导下的全身麻醉深度及管理。方法 选择2016年12月～2017年6月择期胃肠外科开腹手术患者60例，随机分为两组，每组30例，P组为丙泊酚治疗，F组为芬太尼类镇痛药治疗，观察两组基础值，意识消失，插管，插管后30 s，进腹腔，手术结束的BIS、MAP、SBP和HR。结果 两组患者诱导前基础BIS、SBP、MAP、HR，差异无统计学意义(P>0.05)；意识消失时间，意识消失时BIS差异无统计学意义(P>0.05)，意识消失时的丙泊酚用量差异有统计学意义(P<0.05)；两组中，与插管时相比，插管后30 s，进腹腔时BIS、SBP、MAP差异有统计学意义(P>0.05)，HR无统计学意义(P>0.05)；手术结束时两组BIS差异有统计学意义(P>0.05)，HR、SBP、MAP无统计学差异(P>0.05)。结论 临床意义的麻醉深度是具有相对性的，依手术刺激大小而定，麻醉过程中可通过调节麻醉性镇痛药物用量来维持麻醉深度。
关键詞：全身麻醉；麻醉深度；脑电双频普指数
, 百拇医药
中图分类号：R971.2 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.06.024
文章编号：1006-1959(2018)06-0077-03
Study on the Depth of Clinical Anesthesia Guided by Bispectral Index of EEG
YU Xiu-yan1，SANG Tian-ming2，LV Ying-bing1，ZHAO Hong-yu1，YANG Ai-min1
(1.Department of Anesthesiology，Affiliated Hospital of Chengde Medical College，Chengde 067000，Hebei，China；
, 百拇医药
2.Department of Anesthesiology，Longhua County Hospital，Longhua 068150，Hebei，China)
Abstract：Objective To study the depth and management of general anesthesia under the guidance of bispectral index of EEG. Methods 60 patients undergoing elective gastrointestinal surgery from December 2016 to June 2017 were randomly divided into two groups.30 patients in each group，group P was treated with propofol， group F was fentanyl analgesic treatment.The basic values of two groups were observed，consciousness disappeared，intubation，30 s after intubation，abdominal cavity，BIS，MAP，SBP and HR at the end of operation.Results There was no significant difference in baseline BIS，SBP，MAP and HR between the two groups before induction(P> 0.05).There was no significant difference in the time of consciousness disappearance and the loss of consciousness when there was no consciousnes (P>0.05).There was a statistically significant difference in the dosage of propofol when consciousness disappeared(P< 0.05).In two groups，compared with intubation，after intubation 30 s，BIS and SBP into abdominal cavity and MAP had significant difference(P>0.05)，HR had no statistical significance(P>0.05)；at the end of the operation of BIS in the two groups had significant difference(P>0.05)，no significant difference between HR and SBP and MAP(P>0.05).Conclusion The depth of clinical anesthesia is relative，depending on the size of the operation stimulus.During anesthesia，we can adjust the dosage of narcotic analgesics to maintain the depth of anesthesia.
Key words：General anesthesia；Depth of anesthesia；Bispectral index of EEG
现代麻醉中麻醉深度的调控与监测是人们关注的热点话题。对于麻醉深度的研究与讨论，学界内有各种不同观点和分类方法，但尚无一种为大家所接受的理论。随着各种麻醉药物的出现及人们对麻醉药物对人体作用知识体系的改变，单一的麻醉深度含义已经不能满足现代麻醉的要求。麻醉医师需要重新审视和理解麻醉深度的含义，设计麻醉策略，优化麻醉方案，指导临床麻醉。选择2016年12月～2017年6月择期胃肠外科开腹手术患者60例，对麻醉深度的研究，现分析如下。, 百拇医药(于秀燕 桑天明 吕英兵 赵宏玉 杨爱民)
关键詞：全身麻醉；麻醉深度；脑电双频普指数
, 百拇医药
中图分类号：R971.2 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.06.024
文章编号：1006-1959(2018)06-0077-03
Study on the Depth of Clinical Anesthesia Guided by Bispectral Index of EEG
YU Xiu-yan1，SANG Tian-ming2，LV Ying-bing1，ZHAO Hong-yu1，YANG Ai-min1
(1.Department of Anesthesiology，Affiliated Hospital of Chengde Medical College，Chengde 067000，Hebei，China；
, 百拇医药
2.Department of Anesthesiology，Longhua County Hospital，Longhua 068150，Hebei，China)
Abstract：Objective To study the depth and management of general anesthesia under the guidance of bispectral index of EEG. Methods 60 patients undergoing elective gastrointestinal surgery from December 2016 to June 2017 were randomly divided into two groups.30 patients in each group，group P was treated with propofol， group F was fentanyl analgesic treatment.The basic values of two groups were observed，consciousness disappeared，intubation，30 s after intubation，abdominal cavity，BIS，MAP，SBP and HR at the end of operation.Results There was no significant difference in baseline BIS，SBP，MAP and HR between the two groups before induction(P> 0.05).There was no significant difference in the time of consciousness disappearance and the loss of consciousness when there was no consciousnes (P>0.05).There was a statistically significant difference in the dosage of propofol when consciousness disappeared(P< 0.05).In two groups，compared with intubation，after intubation 30 s，BIS and SBP into abdominal cavity and MAP had significant difference(P>0.05)，HR had no statistical significance(P>0.05)；at the end of the operation of BIS in the two groups had significant difference(P>0.05)，no significant difference between HR and SBP and MAP(P>0.05).Conclusion The depth of clinical anesthesia is relative，depending on the size of the operation stimulus.During anesthesia，we can adjust the dosage of narcotic analgesics to maintain the depth of anesthesia.
Key words：General anesthesia；Depth of anesthesia；Bispectral index of EEG
现代麻醉中麻醉深度的调控与监测是人们关注的热点话题。对于麻醉深度的研究与讨论，学界内有各种不同观点和分类方法，但尚无一种为大家所接受的理论。随着各种麻醉药物的出现及人们对麻醉药物对人体作用知识体系的改变，单一的麻醉深度含义已经不能满足现代麻醉的要求。麻醉医师需要重新审视和理解麻醉深度的含义，设计麻醉策略，优化麻醉方案，指导临床麻醉。选择2016年12月～2017年6月择期胃肠外科开腹手术患者60例，对麻醉深度的研究，现分析如下。, 百拇医药(于秀燕 桑天明 吕英兵 赵宏玉 杨爱民)