周黎安 李 谆 郭树忠 艾玉峰 查元坤 鲁开化 高 岚

    (1解放军451医院整形外科 西安710054 2.第四军医大学西京医院整形外科中心 西安710032)

    [摘 要] 目的:观察皮肤伸展作用后生物力学特性和组织学的改变。方法:取4只体重20 kg左右的猪为实验动物,采用自身对照方式进行,对伸展作用侧及对照侧皮肤标本分别进行拉伸断裂强度、拉伸断裂伸长百分率、皮肤本构关系等生物力学指标的测定及组织学的检查。结果:伸展皮肤的粘弹性下降。组织学观察可见伸展后表皮细胞层次增多,真皮层稍变薄。结论:皮肤伸展作用后,其生物力学性质及组织学均有明显变化。临床上可采用皮肤伸展术,以缩短疗程,提高疗效。

    [关键词] 皮肤伸展术 生物力学特性 组织学检查

    [中图分类号]R622 [文献标识码]A [文章编号]1008-6455(2000)09-0244-03

    BIOMECHANICAL AND HISTOMORPHOLOGICAL CHANGES IN STRETCHED PIG SKIN

    ZHOU Li-an LI Zhun GUO Shu-zhong et al

    Depart.Plastic surgery,451 Hospital,(Xian 710054)

    [Abstract] Objective:The study was designed to observe the biomechanical and histomorphological changes in stretched pig skin.Methods:On 4 pigs.stretched skin was compared with non-stretched control skin from the opposite side of the animal,using a paired t-test.The biomechanical and histomorphological properties were determined in stretched and non-stretched control skin.By using tensometer,the sin was evaluated for stress strain and parameters of strength.Result:The biomechanical properties of the stretched skin were different from the control skin.Histomorphological examination revealed that the epidermis layer increase.There was thinning of dermis,the dermal collagen bundles were thicker than those of controle.Conclusion:We concluded that the biomechanical properties and histomorphological changes were different from that of the unstretched skin.It was shown that the skin stretching technique might be accepted in the practice. ......