人参五灵脂配伍对人参补气作用影响的初步药效学研究(1)
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(1.北京王府中西医结合医院,北京 102209;2.求真出版社,北京 100165;
3.涿州市中医院,河北 涿州 070750;4.北京中医药大学,北京 100029)
摘 要:目的:利用现代药理学方法初步探讨十九畏中人参、五灵脂配伍对人参补气作用的影响。方法:以人参单煎液、五灵脂单煎液及人参、五灵脂不同比例配伍混煎液(1∶1、1∶2、2∶1)灌胃给药7天后,观察小鼠游泳时间、耐寒、耐缺氧时间,测定胸腺指数、脾指数及肝糖元含量。结果:配伍组对正常小鼠游泳时间、耐寒、耐缺氧时间及胸腺指数、肝糖元含量均有增强作用(P<0.05),且以人参、五灵脂2∶1配伍组尤为明显,与人参组比较有统计学差异(P<0.05)。结论:研究结果表明,人参与五灵脂配伍对人参补气作用的影响表现为相使配伍,这与传统的理论认识具有明显不同,需要更多的理论和实验支撑。
关键词:人参;五灵脂;配伍;补气
中图分类号:R285.5 文献标识码:A 文章编号:1673-7717(2010)04-0729-03
The Rudiment Pharmacodynamics Study on the Effects of
Compatibility Between Ginseng and Trogopterus Dung on invigorating qi of Ginseng
LIANG Ailing1, GAO Mingjian2, LI Lianjun3,CHEN Shaohong4, ZHONG Gansheng4
(1.Beijing Royal Integrative Medicine Hospital,Beijing 102209,China;
2.Realistic press,Beijing 100165,China;
3.Zhuozhou Hospital of Chinese Medicine in Hebei Province,Zhuozhou 070750,Hebei,China;
4.Beijing University of Chinese Medicine, Beijing 100029,China)
Abstract:Objective:Preliminary study on the effects of Compatibility between Ginseng and Trogopterus Dung on invigorating qi of Ginseng by means of modern pharmacological technique.Methods: Healthy ICR mice were treated by intragastric administration respectively using Ginseng ,Trogopterus dung, Ginseng and fafces trogopterori in the ratio of 1∶1,1∶2,2∶1,and compound salvia tablets.After 7 days,swimming time, Cold resistant time, hypoxia tolerance time were observed; thymus gland index, spleen index and hepatic glycogen content were measured.Results: Compatibility groups could increase swimming time, Cold resistant time, hypoxia tolerance time , thymus gland index and hepatic glycogen content in healthy mice(P<0.05), but Ginseng and fafces trogopterori in the ratio of 2∶1 in particular had significant difference ,compared with Ginseng group(P<0.05).Conclusion:The results indicate that the relation of Compatibility between Ginseng and Trogopterus dung is mutual assistance,this view is different from traditional theory,and still needs more theory and experiments ......
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