针灸治疗肥胖型多囊卵巢综合征的临床疗效观察(1)
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(1.上海市针灸经络研究所,上海 200030;2.上海中医药大学,上海 201203)
摘 要:目的:观察针灸治疗肥胖型多囊卵巢综合征的临床疗效。方法:将40例符合肥胖型多囊卵巢综合征患者根据中医辨证为脾肾阳虚、痰湿阻滞型,采用针刺加隔药灸治疗,观察其体重(BW)、体重指数(BMI)、腰臀比值(WHR)、空腹血糖(FPG)、空腹胰岛素(FINS)、胰岛素敏感指数(ISI)和相关性激素睾酮(testosterone,T)、雌二醇(estradiol, E)及黄体生成素(luteotropic hormone, LH)/卵泡刺激素(follicle stimulating hormone, FSH)比值的变化。结果:临床总有效率为82.5%,BW、BMI、WHR、T及LH/FSH值均有显著降低(P<0.01),E有显著升高(P<0.01),FINS也有一定程度降低,ISI则有所升高(P<0.05)。结论:针灸治疗肥胖型多囊卵巢综合征具有较好的疗效。
关键词:多囊卵巢综合征;肥胖型;针灸疗法;临床研究
中图分类号:R245 文献标识码:B 文章编号:1673-7717(2010)04-0805-03
Clinical study on Acupuncture and Moxibustion Therapy for Polycystic Ovary Syndrome of Obesity Type
SHI Yin1,YU Liqing2,YIN Xiaojun2
(1.Shanghai Institute of Acupuncture-Moxibustion & Meridian,Shanghai 200030, China;
2.Shanghai University of TCM,Shanghai 201203, China)
Abstract:Objective: To observe the effect of PCOS in obesity type by acupuncture and moxibustion therapy. Methods: 40 cases of obese PCOS of kidney and spleen yang deficiency resulting in stagnation of phlegm-damp type were treated with acupuncture and herb-partition moxibustion. The therapeutic effect and levels of body weight(BW), body mass index(BMI), waist-to-hipratio(WHR), fasting plasma glucose(FPG), fasting insulin(FINS), insulin sensitivity index (ISI), testosterone (T), estradiol (E), luteotropic hormone(LH)/ follicle stimulating hormone (FSH) were observed respectively. Results: The total effective rate was 82.5%.There weresignificant difference in the change of related index BW, BMI, WHR, T, E, LH/FSH (P<0.01) and FINS, ISI (P<0.05) after acupuncture and moxibustion therapy to PCOS in obesity type. Conclusion: Acupuncture and moxibustion therapy effect is good for PCOS in obesity type.
Key words:Polycystic ovary syndrome; obesity type; acupuncture and moxibustion therapy; clinical study
收稿日期:2009-11-19
基金项目:上海市重点学科建设项目资助(S30303)
作者简介:施茵(1968-),女,上海人,副主任医师,博士,研究方向:针灸临床效应机制研究。
多囊卵巢综合征(polycystic ovary syndrome,PCOS)是育龄妇女常见的内分泌和代谢功能紊乱性疾病,其病因至今未明,PCOS的临床表现呈现多样性,除症见月经失调(月经稀发甚或闭经)、不孕、多毛、痤疮外,肥胖是患PCOS女性最常见的合并症,肥胖型PCOS发生率为50%[1]。目前针对肥胖型PCOS西医主要以减轻体重为目标,进行包括节食、运动、行为治疗在内的综合治疗;同时针对肥胖型PCOS存在胰岛素抵抗和脂代谢紊乱两大主要病理特征,进行纠正胰岛素抵抗、脂代谢紊乱的药物治疗,但药物治疗肥胖无排卵的作用仅能持续几个疗程,且有副反应 ......
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