胸腺肽α1对脓毒症小鼠CD4+CD25+Foxp3+ T细胞的干预效应(4)
[14] Sakaguchi S, Yamaguchi T, Nomura T, et al. Regulatory T cells and immune tolerance[J]. Cell,2008, 133 (5):775-787.
[15] Askenasy N, Kaminitz A, Yarkoni S. Mechanisms of T regulatory cell function[J]. Autoimmun Rev,2008,8(7):370-375.
[16]Osuchowski MF, Welch K, Siddiqui J, et al. Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality[J]. J Immunol,2006, 177(3):1967-1974.
, http://www.100md.com
[17] Monneret G,Debard AL,Venet F,et a1.Marked elevation of human circulating CD4+CD25+ regulatory T cells in sepsis-induced immunoparalysis[J]. Crit Care Med,2003, 31(7):2068-2071.
[18] Romani L,Bistoni F,Perruccio K. Thymosin α1 activates dendritic cell tryptophan catabolism and establishes a regulatory environment for balance of inflammation and tolerance[J]. Blood,2006,108(7):2265-2274.
[19] Yao WY, Zhu Q,Yuan YZ.Thymosin alpha 1 improves severe acute pancreatitis in rats via regulation of peripheral T cell number and cytokine serum level[J].J Gast Hepat,2007,22(11):1866-1871.
, 百拇医药
[20] Kapoor S. The rapidly expanding therapeutic role of thymosin {alpha}-1 in the management of gastrointestinal and systemic infectious disorders[J]. J Inten Care Med,2009,24(3): 210-211.
[21]Askenasya N,Kaminitza A,Yarkoni S.Mechanisms of T regulatory cell function[J].Autoimmun Rev, 2008,7(5):370-375.
[22] Yolcu ES,Ash S,Kaminitz A. Apoptosis as a mechanism of T-regulatory cell homeostasis and suppression apoptosis in T-regulatory cell homeostasis[J].Immun & Cell Biology,2008,86(8):650-658.
, 百拇医药
[23] 冷凤英,刘嘉林,瞿洪平. 脓毒症患者自然调节性T细胞及可溶性CD25水平研究[J].中华急诊医学杂志,2011,20(2):184-188.
[24] Hotchkiss RS, Opal S. Immunotherapy for sepsis — a new approach against an ancient foe[J]. N Engl J Med,2010, 363(1):87-89.
[25]厉惠莉,章华权. 胸腺肽 α1 联合阿德福韦酯治疗甲胎蛋白升高的慢性乙型肝炎临床观察[J/ CD]. 中华危重症医学杂志:电子版,2010,3(4):259-262.
[26]Huang SW,Guan XD,Chen J,et al. Effect of ulinastatin plus thymosin-α1 therapy on improving immune function in septic patients[J]. Chin J Pathophy, 2009,25(11):2168-2172.
, 百拇医药
(收稿日期:2012-11-13)
(本文编辑:何小军)
DOI:10.3760/cma.j.issn.1671-0282.2013.04.007
基金项目:上海市公共卫生优秀学科带头人培养计划(08GWD21)
作者单位:201100 上海,闵行区中心医院急诊&ICU(万健、邓星奇);第二军医大学上海长征医院急救科(单怡、林兆奋、单红卫、杨兴易)
通信作者:林兆奋,Email:lin_zhaofen@sina.cn
P368-P372
, http://www.100md.com(万健 单怡 林兆奋 邓星奇 单红卫 杨兴易)
[15] Askenasy N, Kaminitz A, Yarkoni S. Mechanisms of T regulatory cell function[J]. Autoimmun Rev,2008,8(7):370-375.
[16]Osuchowski MF, Welch K, Siddiqui J, et al. Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality[J]. J Immunol,2006, 177(3):1967-1974.
, http://www.100md.com
[17] Monneret G,Debard AL,Venet F,et a1.Marked elevation of human circulating CD4+CD25+ regulatory T cells in sepsis-induced immunoparalysis[J]. Crit Care Med,2003, 31(7):2068-2071.
[18] Romani L,Bistoni F,Perruccio K. Thymosin α1 activates dendritic cell tryptophan catabolism and establishes a regulatory environment for balance of inflammation and tolerance[J]. Blood,2006,108(7):2265-2274.
[19] Yao WY, Zhu Q,Yuan YZ.Thymosin alpha 1 improves severe acute pancreatitis in rats via regulation of peripheral T cell number and cytokine serum level[J].J Gast Hepat,2007,22(11):1866-1871.
, 百拇医药
[20] Kapoor S. The rapidly expanding therapeutic role of thymosin {alpha}-1 in the management of gastrointestinal and systemic infectious disorders[J]. J Inten Care Med,2009,24(3): 210-211.
[21]Askenasya N,Kaminitza A,Yarkoni S.Mechanisms of T regulatory cell function[J].Autoimmun Rev, 2008,7(5):370-375.
[22] Yolcu ES,Ash S,Kaminitz A. Apoptosis as a mechanism of T-regulatory cell homeostasis and suppression apoptosis in T-regulatory cell homeostasis[J].Immun & Cell Biology,2008,86(8):650-658.
, 百拇医药
[23] 冷凤英,刘嘉林,瞿洪平. 脓毒症患者自然调节性T细胞及可溶性CD25水平研究[J].中华急诊医学杂志,2011,20(2):184-188.
[24] Hotchkiss RS, Opal S. Immunotherapy for sepsis — a new approach against an ancient foe[J]. N Engl J Med,2010, 363(1):87-89.
[25]厉惠莉,章华权. 胸腺肽 α1 联合阿德福韦酯治疗甲胎蛋白升高的慢性乙型肝炎临床观察[J/ CD]. 中华危重症医学杂志:电子版,2010,3(4):259-262.
[26]Huang SW,Guan XD,Chen J,et al. Effect of ulinastatin plus thymosin-α1 therapy on improving immune function in septic patients[J]. Chin J Pathophy, 2009,25(11):2168-2172.
, 百拇医药
(收稿日期:2012-11-13)
(本文编辑:何小军)
DOI:10.3760/cma.j.issn.1671-0282.2013.04.007
基金项目:上海市公共卫生优秀学科带头人培养计划(08GWD21)
作者单位:201100 上海,闵行区中心医院急诊&ICU(万健、邓星奇);第二军医大学上海长征医院急救科(单怡、林兆奋、单红卫、杨兴易)
通信作者:林兆奋,Email:lin_zhaofen@sina.cn
P368-P372
, http://www.100md.com(万健 单怡 林兆奋 邓星奇 单红卫 杨兴易)