血塞通在中枢神经系统疾病中的应用(综述)

血塞通在中枢神经系统疾病中的应用(1)

http://www.100md.com 2010年2月1日《现代医学》 2010年第1期

     [摘要] 血塞通有效成分为三七总皂甙(PNS),有抗血栓、抗炎消肿、钙通道阻断、清除自由基、保护神经、改善微循环、防止脑血管动脉粥样硬化、镇静镇痛等药理学作用。目前血塞通在临床上广泛应用,尤其在中枢神经系统疾病的治疗中,对脊髓损伤、脑出血、脑缺血后受损神经元有保护作用,对脑梗死、阿尔茨海默病等都有一定的治疗效果。

    [关键词] 血塞通; 三七总皂甙; 中枢神经系统疾病

    [中图分类号] R742; R741.05[文献标识码] A[文章编号] 1671-7562(2010)01-0086-04doi:10.3969/j.issn.1671-7562.2010.01.027

    Application of xuesaitong in the central nervous system diseases

    YANG Ting, JIANG Zan-li, MAO Zu-bin

    (School of Clinical Medicine, Southeast University, Nanjing 210009, China)

    [Abstract] The major effective component part of xuesaitong is panax notoginseng saponin(PNS).It has many pharmacological effects,such as inhibiting the activity of thrombus, reducting edema and inflammation,blocking the Ca2+ channel, eliminating free radical production, protecting the nerve, improving the microcirculation, protecting the cerebrovascular atherosclerosis, making sedation and analgesia. Nowadays PNS is widespread used in the clinic, especially in the therapies of the central nervous system diseases.It has therapeutic effect on the damaged nerve after spinal cord injury, cerebral hemorrhage,cerebral ischemia, cerebral infarction, Alzheimer disease and so on. ......

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