单纯疱疹病毒性脑炎伴Kkuve-Bucy综合征3例(2)
综合文献分析,当患者临床上急性起病,出现发热伴行为异常、贪食、饮食习惯改变、性活动增强、遗忘等KBS表现,头颅MRI显示:双额叶、颞叶炎性病灶,脑电图特征性异常,要首先考虑HSE的诊断,早期治疗预后较好。KBS的有效治疗为镇静剂或卡马西平[2],有不轨行为者给予氯丙嗪。出现贪食者要控制饮食,以防过度饮食导致肥胖,随脑炎的好转,上述症状也好转。
[参考文献]
[1]王新德.神经病毒学—基础与临床[M].北京:人民卫生出版社,2000.377.
[2]Bonno S,Rashilas F, Mari I,et al. Kluve-Bucy syndrome in herpetic meningoencephalitis[J]. Presse Med,2001,30(3):115-118.
[3]Kimberlin K. Herpes simplex virus infections of the central nervous system:encephal it is and meningitis[J].Herpes,2004,2:57-64.
[4]Kluver H,Bucy PC.Preliminary analysis of functions of the temporal lobes in monkeys[J].Arch Neurol Psychiatry,1939,42:979-1000.
[5]Ozawa H,Sasaki M,Sugai K,et al.Single-Photon emission CT and MR findings in Kluver-Bucy syndrome after Reye syndrome[J].AJNR,1997,18:540-542.
[6]Lilly R, Cummings JL,Benson DF,et al.The human KBS[J]. Neurology, 1983,33:1141-1145.
[7]Aygun D,Guven H, Altintop L.Postcontusional Kluver-Bucy syndrome[J].American Journal of Emergency Medicine,2003,21(3):246-247.
(收稿日期:2007-10-15), 百拇医药(姜翠玲 张共青)
[参考文献]
[1]王新德.神经病毒学—基础与临床[M].北京:人民卫生出版社,2000.377.
[2]Bonno S,Rashilas F, Mari I,et al. Kluve-Bucy syndrome in herpetic meningoencephalitis[J]. Presse Med,2001,30(3):115-118.
[3]Kimberlin K. Herpes simplex virus infections of the central nervous system:encephal it is and meningitis[J].Herpes,2004,2:57-64.
[4]Kluver H,Bucy PC.Preliminary analysis of functions of the temporal lobes in monkeys[J].Arch Neurol Psychiatry,1939,42:979-1000.
[5]Ozawa H,Sasaki M,Sugai K,et al.Single-Photon emission CT and MR findings in Kluver-Bucy syndrome after Reye syndrome[J].AJNR,1997,18:540-542.
[6]Lilly R, Cummings JL,Benson DF,et al.The human KBS[J]. Neurology, 1983,33:1141-1145.
[7]Aygun D,Guven H, Altintop L.Postcontusional Kluver-Bucy syndrome[J].American Journal of Emergency Medicine,2003,21(3):246-247.
(收稿日期:2007-10-15), 百拇医药(姜翠玲 张共青)