[摘要] 目的：研究输注或口服头孢类抗生素后饮酒出现双硫醒反应的发病机制，为防止再次出现此反应提供依据。方法：对16例出现双硫醒反应的病例进行临床分析。结果：乙醛在体内蓄积致双硫醒反应，引起一系列临床症状与体征：面色潮红、出汗、胸闷、心悸、气短感，心电图示窦性心动过速等；经对症治疗后病情可缓解。结论：应高度重视输注或口服头孢类抗生素后饮酒出现的双硫醒反应，在应用头孢类抗生素期间或停药后1周内避免饮酒。

    [关键词] 头孢类；饮酒；双硫醒反应

    [中图分类号]R45 [文献标识码]C [文章编号]1673-7210(2008)02(c)-152-02

    16 cases with the abstinyl reaction caused by drinking while using the cephalosporin antibiotic

    ZHENG Zhi-jie

    (The 3rd People's Hospital of Cangnan,Zhejiang Province,Cangnan 325804,China)

    [Abstract] Objective: To study the pathogenesis of abstinyl reaction caused by drinking while infecting or taking orally the cephalosporin antibiotic. Preventing the recurrence of such reaction and providing a basis for the reaction.Methods: Clinical analysis of the 16 cases with abstinyl reaction.Results: The pathogenesis was that the ethyl alcohol stores up in the body and causes a series of clinical symptoms and signs, such as facial flushing, sweating, chest stuffiness, palpitation, panting, electrocardiogram showing Dou tachycardia and so on. We could alleviate the illness by symptomatic treatment.Conclusion: We should attach great importance to the reaction and avoid drinking while using the cephalosporin antibiotic or after the drug withdrawal within a week. ......