连花清瘟胶囊治疗甲型H1N1流感的临床研究(1)
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[摘要] 目的：观察连花清瘟胶囊治疗甲型H1N1流感的疗效及安全性。方法：随机对照分析2009年9月～2010年3月应用连花清瘟胶囊、奥司他韦胶囊、氨咖黄敏胶囊治疗甲型H1N1流感患者174例，对比观察连花清瘟胶囊的体温疗效、证候疗效、退热起效时间以及不良反应。结果：体温疗效显效率连花清瘟组和奥司他韦组分别为72.4%、75.7%，两组之间无显著性差异(P>0.05)，均明显高于氨咖黄敏组(48.3%)(P<0.05)；临床证候的显效率连花清瘟组和奥司他韦组分别为75.9%、79.3%，两组之间无显著性差异(P>0.05)，均明显高于氨咖黄敏组(55.2%)(P<0.05)；连花清瘟组退热起效时间优于奥司他韦组(P=0.032)；三组不良反应发生率均较低。结论：连花清瘟胶囊治疗甲型H1N1流感与奥司他韦一样效果显著，安全性好。
[关键词] 甲型H1N1流感；连花清瘟胶囊；奥司他韦；氨咖黄敏
[中图分类号] R511.7[文献标识码]A [文章编号]1673-7210(2010)10(c)-006-03
Clinical observation of Lianhua Qingwen Department of Emergency, Capsules in treatment of the influenza A/H1N1
OUYANG Huixiang, TANG Qingyan, CHEN Yongzhong, WEI Yu, LI Guoshu
(Department of Emergency, Central Hospital of Hengyang City, Hengyang 421001, China)
[Abstract] Objective: To observe the clinical effect and safety of Lianhua Qingwen Capsules in treatment of the influenzaA/H1N1. Methods: The data of 174 admitted patients with the influenza A/H1N1 who were treated with Lianhua Qingwen Capsules, Oseltamivir Capsules, Paracetamol, Caffein, Atificial Cow-bezoar and Chlorphenamine Maleate Capsules from September 2009 to March 2010 was randomly collected. The effective rate of temperature effect test, TCM symptoms test and side effects of Lianhua Qingwen Capsules were compared. Results: The effective rate of temperature effect test in Lianhua Qingwen Capsules group and Oseltamivir Capsules group were 72.4% and 75.7%， showing no significant difference(P>0.05)，which was significantly higher than that (48.3%) in Paracetamol, Caffein, Atificial Cow-bezoar and Chlorphenamine Maleate Capsules group (P<0.05); the effective rate of TCM symptoms test in Lianhua Qingwen Capsules group and Oseltamivir Capsules group were 75.9% and 79.3%，showing no significant difference (P>0.05)，which was significantly higher than that (55.2%) in Paracetamol, Caffein, Atificial Cow-bezoar and Chlorphenamine Maleate Capsules group (P<0 ......
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