当前位置: 首页 > 期刊 > 《医药产业资讯》 > 2010年第30期 > 正文
编号:11975054
子宫内膜与卵巢双原发癌病理诊断分析(1)
http://www.100md.com 2010年10月25日 张艳玲,赵小华
第1页

    参见附件(3174KB,4页)。

     [摘要] 目的:探讨子宫内膜与卵巢双原发癌的临床病理特点。方法:回顾性分析15例子宫内膜与卵巢双原发癌的临床病理资料。结果:15例子宫内膜与卵巢双原发癌中,12例(80%)诊断正确,早期3例(20%)误诊为子宫内膜癌伴卵巢转移,误诊的主要原因是早期对子宫内膜与卵巢原发性双癌的认识不足,没有结合临床资料、影像表现、病理特点进行综合分析。结论:临床、影像、病理三项结合,子宫与卵巢双原发癌不难诊断。

    [关键词] 子宫内膜癌;卵巢癌;双原发癌;临床病理特点

    [中图分类号] R737.33[文献标识码]A[文章编号]1674-4721(2010)10(c)-014-04

    The pathologic diagnosis and analysis for double primary cancer of endometrium and ovary

    ZHANG Yanling1, ZHAO Xiaohua2

    (1.Department of Pathology, Longjiang Hospital of Shunde District, Foshan City, Foshan 528318, China; 2.Department of Radiology, Longjiang Hospital of Shunde District, Foshan City, Foshan 528318, China)

    [Abstract] Objective: To investigate the clinical and clinicopathological characteristics of synchronous primary cancers of the endometrium and ovary. Methods: The clinicopathological data of 15 patients with synchronous primary cancers of the endometrium and ovary were retrospectively reviewed. Results: 12 patients (80%) were diagnosed to be correctly of 15 patients with synchronous primary cancers of the endometrium and ovary, 3 patients (20%) who were misdiagnosed as the cancers of endometrium in early stage had ovarian metastasis, the reason of misdiagnosis was short of the knowledge about synchronous primary cancers of endometrium and ovary, to analyze diagnosis without the clinical data, the representation of medical imaging and clinicopathological characteristics. Conclusion: If we undertake a comprehensive analysis with clinic, medical imaging, pathological characteristics, the diagnosis of synchronous primary cancers of the endometrium and ovary will not be difficult.

    [Key words] Endometrium carcinoma; Ovary carcinoma; Synchronous primary cancers; Clinicopathological characteristics

    子宫内膜与卵巢双原发癌在临床中少见。笔者对15例子宫内膜与卵巢双原发癌的临床资料、影像表现、病理特点进行了观察和分析,结合文献总结如下:

    1 资料与方法

    1.1 一般资料

    收集1992~2009年临床病理资料完整的15例子宫内膜与卵巢双原发癌,全部病例均经省级以上妇产科病理专家会诊。

    1.2 病理切片

    标本均用4%中性甲醛液固定,常规石蜡切片,4 μm厚,HE染色。

    1.3 诊断标准

    本组病例诊断以Soliman等[1]和Young等[2]提出的子宫内膜与卵巢双原发癌诊断标准:①两个癌灶无直接的联系;②通常无子宫肌层浸润或仅有浅表的肌层浸润;③无淋巴和血管内的浸润;④肿瘤主要存在于卵巢和子宫内膜;⑤两个肿瘤常局限于原发灶,或仅伴微小转移;⑥常伴有子宫内膜不典型增生;⑦卵巢内有时伴有子宫内膜异位症;⑧两个肿瘤的组织学类型可以是相同的,也可以是不同的。

    1.4 临床表现

    15例患者均已婚,平均年龄为48.7岁(29~72岁),均无肿瘤家族史及口服避孕药和雌激素史。原发不孕3例,阴道不规则出血8例,盆腹腔疼痛6例,卵巢内膜异位症2例。子宫内膜和卵巢均为内膜样腺癌的患者11例,平均年龄为42.3岁(29~63岁),未育4例,肥胖者7例。

    1.5 影像学检查

    15例均行B超检查,发现盆腔肿块9例(60.0%),子宫内膜增厚或异常回声4例(26.7%),子宫腔积液1例(6.7%),腹水3例(20.0%)。11例患者行CT检查 ......

您现在查看是摘要介绍页,详见PDF附件(3174KB,4页)