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异丙酚联合瑞芬太尼清醒镇静对呼吸功能的影响(3)
http://www.100md.com 2008年7月22日 《中国实用医药》 2008年第16期
异丙酚联合瑞芬太尼清醒镇静对呼吸功能的影响

     本研究中瑞芬太尼组的呼吸频率[9]研究结果相似,但远远低于Servin等 [10]报道。我们在研究中给患者常规鼻导管吸氧的情况下,血氧饱和度曾低于95%的发生率仅为25%,只是采取呼唤患者让患者深呼吸或面罩吸氧[11],即能快速收到明显效果,没有采取进一步的辅助措施即调整药物剂量或辅助通气。

    综上所述瑞芬太尼复合异丙酚静脉输注能够给腰硬联合麻醉下行子宫切除术的患者提供有效的清醒镇静,能够提供安全的呼吸功能保证。

    参 考 文 献

    [1] Scammman FL,Klein SL,Choi WW.Conscious sedation for procedures under local or topical anesthesia.Ann Otol Rhinol Laryngol,1985,94:21-24.

    [2] 刘萍,杨钰香,姚尚龙,等.咪达唑伦靶控输注系统用于臂丛神经阻滞病人清醒镇静的研究.中华麻醉学杂志,2003,23(4):297-298.

    [3] 宗明江,赵豫华,周丽萍,等.咪唑安定或丙泊酚伍用芬太尼对镇静深度和呼吸、循环的影响.临床麻醉学杂志,2005,21(1):13-16.

    [4] Blouin RT,Seifert HA,Babenco HD,et al.Propofol depress hypoxic ventilatory response during conscious sedation and isohypercapnia.Anesthesiology,1993,79:1177-1182.

    [5] McHardy FE,Fortier J,Chung F,et al.A comparison of midazolam,alfentanil and propofol for sedation in outpatient intraocular surgery.Can J Anaesth,2000,47:211-214.

    [6] Yamakage M,Kamada Y,Toriyabe,et al.Changes in respiratory pattern and arterial blood gases during sedation with propofol or midazolam in spinal anesthesia.J Clin Anesth,1999,11:375-379.

    [7] Berkenbosch A,Teppema LJ,Olievier CN,et al.Influences of morphine on the ventilatory response to isocapnic hypoxia.Anesthesiology,1997,86:1342-1349.

    [8] Holas A,Krafft P,Marcovic M,et al.Remifentanil,propofol or both for conscious sedation during eye surgery under regional anaesthesia.European Journal of Anaesthesiology,1999,16:741-748.

    [9] Krenn H,Deusch E,Jellinek H,et al.Remifentanil or propofol for sedation during carotid endarterectomy under cervical plexus block.Br J Anaesth,2002,89:637-640.

    [10] Servin FS,Raeder JC,Merle JC,et al.Remifentanil sedation compared with propofol during regional anaesthesia.Acta Anaesthesiol Scand,2002,46:309-315.

    [11] Rewari V,Madan R,Kaul HL,et al.Remifentanil and propofol sedation for retrobulbar nerve block.Anaesth Intensive Care,2002,30:433-437., http://www.100md.com(仪福霞 纪凡层 崔素梅)
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